Clinical Trials Directory

Trials / Completed

CompletedNCT00004284

Phase III Randomized, Double-Blind Study of Potassium Phosphate Vs Potassium Citrate for Absorptive Hypercalciuria

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
300 (planned)
Sponsor
National Center for Research Resources (NCRR) · NIH
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

OBJECTIVES: I. Evaluate the ability of a slow-releasing formulation of neutral potassium phosphate to correct hypercalciuria and prevent recurrent stone formation in patients with absorptive hypercalciuria. II. Evaluate the safety of this treatment. III. Compare the efficacy of potassium phosphate to that of potassium citrate.

Detailed description

PROTOCOL OUTLINE: This is a randomized, double-blind study. Patients are stratified by participating institution. Patients receive potassium phosphate or potassium citrate tablets twice a day for 3 years.

Conditions

Interventions

TypeNameDescription
DRUGpotassium citrate
DRUGpotassium phosphate

Timeline

Start date
1995-04-01
First posted
1999-10-19
Last updated
2005-06-24

Source: ClinicalTrials.gov record NCT00004284. Inclusion in this directory is not an endorsement.