NCT00003404

Radiation Therapy After Surgery in Treating Women With Phyllodes Tumor of the Breast

A Prospective Study of Adjuvant Radiation Therapy After Resection of Borderline and Malignant Phyllodes Tumors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Dartmouth-Hitchcock Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 120 Years
• Healthy volunteers: Not accepted

Summary

PURPOSE: This phase II trial studied how well radiation therapy works after surgery in treating women with phyllodes tumor of the breast. RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Radiation therapy following surgery may be effective in treating patients with phyllodes tumor of the breast.

Detailed description

OBJECTIVES: * Determine the local recurrence rate in women with phyllodes tumors of the breast previously treated with local excision with negative margins and are now treated with adjuvant radiotherapy. * Determine the survival rate in patients treated with this regimen. METHODS: Within 12 weeks after prior local excision or breast reexcision, patients underwent adjuvant radiotherapy 5 days a week for a total of 28 treatments. Patients were then followed every 6 months for 10 years.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
RADIATION	Adjuvant Radiotherapy	Adjuvant radiation therapy

Timeline

• Start date: 1998-01-01
• Primary completion: 2008-11-17
• Completion: 2008-11-17
• First posted: 2003-01-27
• Last updated: 2019-01-22
• Results posted: 2019-01-22

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study