NCT00003092

Paclitaxel in Treating Older Patients With Solid Tumors

Clinical Pharmacology of Paclitaxel in Relation to Patient Age

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Alliance for Clinical Trials in Oncology · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase III trial to study the effectiveness of paclitaxel in treating older patients who have solid tumors.

Detailed description

OBJECTIVES: * Determine whether there is a relationship between pharmacokinetic measurements of paclitaxel and aging. * Determine whether there is a relationship between the toxic effects of paclitaxel and aging. OUTLINE: Patients are stratified according to age (cohort 1: patients 55 to 64 vs cohort 2: patients 65 to 75 vs cohort 3: patients 75 and over).

Conditions

• Unspecified Adult Solid Tumor, Protocol Specific

Interventions

Type	Name	Description
DRUG	paclitaxel

Timeline

• Start date: 1997-09-01
• Primary completion: 2006-03-01
• Completion: 2006-06-01
• First posted: 2003-01-27
• Last updated: 2016-07-14

Locations

32 sites across 1 country: United States