Clinical Trials Directory

Trials / Completed

CompletedNCT00002159

A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
60 (planned)
Sponsor
Janssen, LP · Industry
Sex
All
Age
13 Years
Healthy volunteers
Not accepted

Summary

To assess the safety of intravenous itraconazole compared to amphotericin B in HIV positive or negative persons with blastomycosis or histoplasmosis.

Detailed description

Patients are randomized to receive IV itraconazole for 2 days, then either itraconazole daily for 5 days or amphotericin B daily for 7 days. IV treatment is followed by consolidation with oral itraconazole for up to 1 year.

Conditions

Interventions

TypeNameDescription
DRUGItraconazole
DRUGAmphotericin B

Timeline

First posted
2001-08-31
Last updated
2005-06-24

Locations

9 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00002159. Inclusion in this directory is not an endorsement.