Clinical Trials Directory

Trials / Completed

CompletedNCT00001680

A Pilot Trial of Topical Thalidomide for the Management of Chronic Discoid Lupus Erythematosus

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
17 (planned)
Sponsor
National Cancer Institute (NCI) · NIH
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The purpose of this double-masked, pilot trial is to determine whether 20 percent thalidomide ointment is safe and effective for the treatment of chronic discoid lupus erythematosus (CDLE) when used under an occlusive dressing. Seventeen patients with two similar lesions will have lesions randomized to receive either intervention or placebo therapy.

Detailed description

The purpose of this double-masked, pilot trial is to determine whether 20 % thalidomide ointment is safe and effective for the treatment of chronic discoid lupus erythematosus (CDLE) when used under an occlusive dressing. Seventeen patients with two similar lesions will have lesions randomized to receive either intervention or placebo therapy.

Conditions

Interventions

TypeNameDescription
DRUGThalidomide

Timeline

Start date
1997-10-01
Completion
2001-07-01
First posted
2002-12-10
Last updated
2008-03-04

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00001680. Inclusion in this directory is not an endorsement.