| Completed | A Study to Characterize Single and Repeat Dose Pharmacokinetics of Tebipenem-Pivoxil-Hydrobromide (TBP-PI-HBr) Healthy Participants | Phase 1 | 2024-11-20 |
| Completed | A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Par Urinary Tract Infection, Acute Pyelonephritis | Phase 3 | 2023-12-21 |
| Completed | A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Etham Healthy Volunteers | Phase 1 | 2023-08-04 |
| Completed | A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Linin Healthy Volunteer | Phase 1 | 2023-08-01 |
| Completed | A Study to Compare Two Bioanalytical Assays for Tebipenem Healthy Volunteers | Phase 1 | 2023-05-04 |
| Completed | A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placeb Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD) | Phase 2 | 2022-12-14 |
| Completed | Phase 1 Study of PK and Safety of SPR206 in Subjects With Various Degrees Of Renal Function Renal Impairment | Phase 1 | 2021-06-08 |
| Completed | Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers Healthy Volunteers | Phase 1 | 2021-06-03 |
| Completed | Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid Healthy Volunteers | Phase 1 | 2020-12-07 |
| Terminated | Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Mycobacterium Avium Complex, Non-tuberculous Mycobacterium Pulmonary Disease | Phase 2 | 2020-12-03 |
| Completed | Study of the Absorption, Metabolism, and Excretion of [14C]-Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) Follo Healthy Volunteers | Phase 1 | 2020-09-30 |
| Completed | Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Healthy Volunteers | Phase 1 | 2020-07-01 |
| Completed | Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Heal Healthy Volunteers | Phase 1 | 2020-06-01 |
| Completed | Effect of Tebipenem on Normal Human Intestinal Microbiota Healthy Volunteers | Phase 1 | 2020-02-10 |
| Completed | A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the E TQT Study | Phase 1 | 2020-01-19 |
| Completed | Phase 1 Study of PK and Safety of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Subjects With Various Degree Renal Impairment | Phase 1 | 2019-12-06 |
| Completed | Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromid Complicated Urinary Tract Infection, Acute Pyelonephritis | Phase 3 | 2019-06-03 |
| Completed | A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers Healthy Volunteers | Phase 1 | 2018-12-18 |
| Completed | A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR206 in Healthy Volunt Healthy Volunteers | Phase 1 | 2018-12-18 |
| Completed | Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741 Healthy Volunteers | Phase 1 | 2017-11-10 |
| Completed | Phase 1 Study of Safety, Tolerability and Pharmacokinetics of SPR994 Healthy Volunteers | Phase 1 | 2017-10-20 |
| Completed | A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR741 in Healthy Volunt Healthy Volunteers | Phase 1 | 2016-12-01 |