| Suspended | A Study of Poziotinib in Previously Treated Participants With Locally Advanced or Metastatic NSCLC Harboring H NSCLC | Phase 3 | 2022-05-12 |
| Recruiting | A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumo Solid Tumors, Lymphoma | Phase 2 | 2021-05-20 |
| Completed | A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Healthy | Phase 1 | 2021-04-08 |
| Withdrawn | A Study of IGN002 for Refractory NHL NHL | Phase 1 | 2021-01-01 |
| Terminated | Study of Poziotinib in Japanese Patients With NSCLC NSCLC | Phase 1 / Phase 2 | 2020-06-23 |
| Completed | Study of the Absorption, Metabolism, and Excretion Following a Single Dose of [14C]-Poziotinib in Healthy Male Healthy | Phase 1 | 2020-05-29 |
| Completed | Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Neutropenia, Breast Cancer | Phase 1 | 2020-03-11 |
| Terminated | A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Facto Breast Cancer, Colorectal Cancer, Solid Tumor | Phase 2 | 2019-12-23 |
| Terminated | A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment Solid Tumor | Phase 1 | 2019-06-25 |
| Terminated | A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib NSCLC, Breast Cancer | Phase 2 | 2018-10-05 |
| Terminated | A Study of Poziotinib in Combination With T-DM1 in HER2-Positive Breast Cancer Breast Cancer | Phase 1 | 2018-07-13 |
| Terminated | Phase 2 Study of Poziotinib in Participants With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation NSCLC | Phase 2 | 2017-10-13 |
| Terminated | A Study of Intravesical Qapzola (Apaziquone) as a Surgical Adjuvant in Participants Undergoing Transurethral R Bladder Cancer | Phase 3 | 2017-08-04 |
| Completed | Pharmacokinetics of SPI-2012 (Eflapegrastim) in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamid Breast Cancer, Pharmacokinetics | Phase 1 | 2017-05-11 |
| Completed | SPI-2012 vs Pegfilgrastim in Management of Neutropenia in Breast Cancer Participants With Docetaxel and Cyclop Neutropenia, Breast Cancer | Phase 3 | 2017-05-10 |
| Terminated | Phase 1, Dose-Escalation Study of IGN002 in NHL Subjects Non-Hodgkin Lymphoma | Phase 1 | 2016-05-01 |
| Completed | Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer Breast Cancer | Phase 2 | 2016-02-22 |
| Completed | SPI-2012 vs Pegfilgrastim in the Management of Neutropenia in Participants With Breast Cancer With Docetaxel a Neutropenia, Breast Cancer | Phase 3 | 2016-01-19 |
| Terminated | A Study of Intravesical Apaziquone as a Surgical Adjuvant in Participant Undergoing Transurethral Resection Bl Bladder Cancer | Phase 3 | 2015-10-09 |
| Terminated | Study of SPI-1620 in Combination With Docetaxel Versus Docetaxel Alone for Patients With Non Small-cell Lung C Non Small Cell Lung Cancer (NSCLC) | Phase 2 | 2013-05-01 |
| Terminated | Phase II Study of SPI-1620 in Combination With Docetaxel as a Second-Line to Treat Biliary Cancer Biliary Cancer | Phase 2 | 2013-04-01 |
| Completed | Phase 2 Study of SPI-2012 or Pegfilgrastim for the Management of Neutropenia in Participants With Breast Cance Neutropenia | Phase 2 | 2013-03-25 |
| Terminated | Rituximab or Zevalin - Efficacy Trial of Therapeutic Alternatives (RoZetta) Follicular Lymphoma | Phase 3 | 2012-12-11 |
| Terminated | Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme | Phase 2 | 2012-06-19 |
| Terminated | Study of Zevalin Versus Observation in Participants at Least 60 Years Old With Newly Diagnosed Diffuse Large B Diffuse Large B-cell Lymphoma, Follicle Center Lymphoma | Phase 3 | 2012-04-19 |
| Completed | Study to Assess the Safety and the Phosphate Binding Capacity of Renazorb Safety, Phosphate Binding Capacity | Phase 1 | 2012-04-01 |
| Terminated | A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL Acute Lymphoblastic Leukemia (ALL) | Phase 3 | 2012-03-01 |
| Terminated | Efficacy and Safety Study of Apaziquone vs. Placebo in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC Bladder Cancer | Phase 3 | 2012-01-01 |
| Terminated | Phase 2 Study of Zevalin Versus Zevalin and Motexafin Gadolinium in Patients With Rituximab-Refractory Low-gra Non-Hodgkin's Lymphoma | Phase 2 | 2011-11-01 |
| Terminated | Pralatrexate vs Observation Following CHOP-based Chemotherapy in Undiagnosed Peripheral T-cell Lymphoma Patien Peripheral T-cell Lymphoma | Phase 3 | 2011-08-01 |
| Terminated | Efficacy and Safety of Multi-Instillations of Apaziquone in Patients With Non-Muscle Invasive Bladder Cancer Bladder Cancer | Phase 3 | 2011-07-01 |
| Completed | A Study of Belinostat in Combination With Warfarin in Patients With Solid Tumors or Hematological Malignancies Solid Tumor, Hematological Malignancy | Phase 1 | 2010-12-01 |
| Completed | International,Multi-Center,Open Label,Randomized Study Assessing the Safety and Efficacy of a Monthly Dosing R Prostate Cancer | Phase 2 | 2010-11-01 |
| Completed | Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma Lymphoma, B-Cell | Phase 2 | 2009-09-01 |
| Completed | Belinostat in Relapsed or Refractory Peripheral T-Cell Lymphoma Peripheral T-cell Lymphoma | Phase 2 | 2008-12-15 |
| Terminated | Trial of the Safety and Efficacy of Ozarelix in Participants With Benign Prostatic Hyperplasia (BPH) Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptoms (LUTS) | Phase 2 | 2008-12-04 |
| Completed | Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumor Small Cell Lung Cancer, Ovarian Cancer, Solid Tumors | Phase 1 | 2008-11-10 |
| Completed | Zevalin Post-marketing Surveillance in Japan Non-Hodgkin's Lymphoma (NHL) | — | 2008-09-01 |
| Completed | Safety, Tolerability and Systemic Absorption of Menadione Topical Lotion for Epidermal-Growth-Factor-Receptor EGFR Inhibitor-associated Rash | Phase 1 | 2008-04-03 |
| Withdrawn | A Study to Assess the Safety and Preliminary Efficacy of PT-523 in Patients With Advanced Non-Small Cell Lung Non-Small-Cell Lung Carcinoma | Phase 1 / Phase 2 | 2008-04-01 |
| Completed | Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treat Non-small Cell Lung Cancer | Phase 2 | 2008-01-01 |
| Completed | A Phase I, Open-label, Ascending Dose Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Carcinoma | Phase 1 | 2008-01-01 |
| Terminated | Study of RH-1 in Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma Advanced Solid Tumors, Non-Hodgkin's Lymphoma | Phase 1 | 2007-11-01 |
| Completed | Safety and Efficacy of Marqibo in Metastatic Malignant Uveal Melanoma Metastatic Malignant Uveal Melanoma | Phase 2 | 2007-11-01 |
| Completed | Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer Bladder Cancer | Phase 3 | 2007-08-01 |
| Completed | Safety and Efficacy of Marqibo in Relapsed Acute Lymphoblastic Leukemia Acute Lymphoblastic Leukemia (ALL) | Phase 2 | 2007-05-01 |
| Completed | Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer Bladder Cancer | Phase 3 | 2007-04-01 |
| Completed | The Safety and Efficacy of Ozarelix to Treat Men With Lower Urinary Tract Symptoms Due to Enlargement of the P Benign Prostatic Hypertrophy | Phase 2 | 2007-01-23 |
| Terminated | Phase 3 Study of Zevalin Following R-CVP in Previously Untreated Patients With Follicular Non Hodgkin's Lympho Follicular Lymphoma, Lymphoma, Follicular | Phase 3 | 2006-10-01 |
| Completed | Study of Vinorelbine Liposomes Injection for Advanced Solid Tumors, Non-Hodgkin's Lymphoma or Hodgkin's Diseas Tumors, Hodgkins Disease, Non-Hodgkins Lymphoma | Phase 1 | 2006-07-01 |
| Terminated | Study Comparing Zevalin Regimen With no Further Treatment in Patients With Diffuse Large B-cell Lymphoma. Lymphoma, Large Cell, Diffuse | Phase 3 | 2006-05-01 |
| Withdrawn | A Study to Evaluate PT-523 in Patients With Refractory Leukemia Leukemia | Phase 1 / Phase 2 | 2005-07-01 |
| Completed | Phase II Trial of EOquin in High-risk Superficial Bladder Cancer Bladder Neoplasms | Phase 2 | 2005-07-01 |
| Completed | Elsamitrucin (SPI 28090) for Relapsed or Refractory Non-Hodgkin's Lymphoma Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | 2004-04-01 |
| Terminated | Safety Study of PT-523 in Cancer Patients to Treat Solid Tumors Including a Preliminary Assessment of Effectiv Neoplasms | Phase 1 | 2004-03-01 |
| Completed | Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast C Breast Cancer, Metastases | Phase 3 | 2004-02-01 |
| Withdrawn | Chemotherapy and Radiation Therapy With or Without Efaproxiral in Treating Patients With Stage III Non-Small C Lung Cancer | Phase 3 | 2002-11-01 |
| Completed | 10-Propargyl-10-Deazaaminopterin in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or H Lymphoma | Phase 1 / Phase 2 | 2002-08-01 |
| Completed | Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases Metastatic Cancer | Phase 3 | 2000-02-01 |
| Completed | Combination Chemotherapy, Radiation Therapy, and RSR13 in Treating Patients With Stage III Non-small Cell Lung Lung Cancer | Phase 2 | 1998-10-01 |