| Recruiting | SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioend Epithelioid Hemangioendothelioma (EHE) | Phase 2 | 2026-02-24 |
| Recruiting | A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma HLA-A*0201 Positive Cells Present, Clear Cell Sarcoma (CCS) | Phase 2 | 2025-10-22 |
| Active Not Recruiting | SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST Gastrointestinal Stromal Tumors, GIST | Phase 2 | 2024-08-01 |
| Active Not Recruiting | SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma Advanced Dedifferentiated Liposarcoma | Phase 3 | 2021-11-11 |
| Active Not Recruiting | SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma Osteosarcoma, Osteosarcoma in Children, Osteosarcoma Recurrent | Phase 2 | 2021-06-04 |
| Completed | SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarc Ewing Sarcoma | Phase 1 / Phase 2 | 2021-01-05 |
| Completed | SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients Wit Malignant Peripheral Nerve Sheath Tumors, Neurofibromatosis 1 | Phase 2 | 2019-10-02 |
| Active Not Recruiting | A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Soft Tissue Sarcoma of the Extremity | Phase 2 | 2017-07-19 |
| Withdrawn | SARC029: Trametinib and Pazopanib in Patients With GIST (Gastrointestinal Stromal Tumor) Gastrointestinal Stromal Tumors | Phase 2 | 2017-01-01 |
| Completed | SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic Leiomyosarcoma Metastatic Leiomyosarcoma | Phase 2 | 2015-11-12 |
| Completed | SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas Soft Tissue Sarcoma, Bone Sarcoma | Phase 2 | 2015-03-01 |
| Completed | SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes Liposarcoma, Osteogenic Sarcoma, Ewing/Ewing-like Sarcoma | Phase 2 | 2014-07-01 |
| Completed | ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temoz Ewing Sarcoma | Phase 1 | 2014-05-01 |
| Completed | SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors) Malignant Peripheral Nerve Sheath Tumors (MPNST), Sarcoma | Phase 1 / Phase 2 | 2013-12-01 |
| Completed | SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors Malignant Peripheral Nerve Sheath Tumors, MPNST, Sarcoma | Phase 2 | 2012-09-01 |
| Terminated | Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors ( Gastrointestinal Stromal Tumors | Phase 3 | 2010-01-01 |
| Terminated | A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the L Osteosarcoma | Phase 2 | 2009-03-01 |
| Completed | Trial of Dasatinib in Advanced Sarcomas Rhabdomyosarcoma, Malignant Peripheral Nerve Sheath Tumors, Chondrosarcoma | Phase 2 | 2007-05-01 |
| Completed | Gemcitabine and Docetaxel in Treating Patients With Recurrent Osteosarcoma (Closed to Accrual as of 12/21/06) Sarcoma | Phase 2 | 2006-10-01 |
| Completed | Neoadjuvant Imatinib in Dermatofibrosarcoma Protuberans Dermatofibrosarcoma Protuberans | Phase 2 | 2006-05-01 |
| Completed | Adjuvant Chemotherapy for High Risk Uterine Leiomyosarcoma Leiomyosarcoma, Uterine Neoplasm | Phase 2 | 2006-01-01 |
| Completed | Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tum Neurofibromatosis Type 1, Sarcoma | Phase 2 | 2005-12-01 |
| No Longer Available | SARC021C: A Continuation Study of TH-CR-406/SARC021 Soft Tissue Sarcoma | — | — |