| Not Yet Recruiting | L19IL2/TNF in Patients With Basal Cell Carcinoma Locally Advanced Basal Cell Carcinoma | Phase 2 | 2026-02-01 |
| Not Yet Recruiting | L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma Locally Advanced Cutaneous Squamous Cell Carcinoma | Phase 2 | 2026-02-01 |
| Not Yet Recruiting | L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC) Locally Advanced Basal Cell Carcinoma | Phase 2 | 2026-02-01 |
| Not Yet Recruiting | A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent Glioma | Phase 2 | 2026-01-30 |
| Recruiting | A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis Rheumatoid Arthritis (RA) | Phase 1 | 2026-01-01 |
| Recruiting | A Study to Evaluate the Safety and Preliminary Signs of Efficacy of [177Lu]Lu-OncoFAP-23 Alone or in Combinati FAP | Phase 1 | 2025-10-31 |
| Completed | A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoCAIX in Patients With CAIX-positive Cancer Clear Cell Renal Cell Carcinoma (ccRCC) | Phase 1 | 2025-04-16 |
| Completed | A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoACP3 in Patients With Prostate Cancer Prostate Cancer, Prostate Cancer Metastatic Disease, PSA Level Greater Than 0.2 | Phase 1 | 2025-04-08 |
| Recruiting | Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Melanoma Stage III, Melanoma Stage IV | Phase 2 | 2024-07-12 |
| Recruiting | A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence Glioblastoma | Phase 2 | 2024-05-22 |
| Completed | A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors Breast Cancer, Colorectal Cancer, Oesophageal Cancer | Phase 1 | 2023-04-27 |
| Withdrawn | Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment Rheumatoid Arthritis | Phase 1 | 2023-03-31 |
| Unknown | L19IL2/L19TNF in Skin Cancer Patients BCC - Basal Cell Carcinoma, SCC - Squamous Cell Carcinoma, Merkel Cell Carcinoma | Phase 2 | 2023-03-09 |
| Withdrawn | Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Pr Glioblastoma | Phase 1 | 2022-06-01 |
| Recruiting | A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progre Glioblastoma | Phase 1 / Phase 2 | 2021-02-19 |
| Recruiting | Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastom Glioblastoma | Phase 1 / Phase 2 | 2021-01-20 |
| Unknown | Intratumoral Administration of Daromun in Non-melanoma Skin Cancer Patients Carcinoma, Basal Cell, Carcinoma, Cutaneous Squamous Cell | Phase 2 | 2020-09-02 |
| Active Not Recruiting | Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sar Soft Tissue Sarcoma | Phase 2 | 2020-08-28 |
| Recruiting | Safety and Early Signs of Efficacy of IL12-L19L19. Advanced Solid Tumor, Metastatic Solid Tumor | Phase 1 | 2020-07-01 |
| Active Not Recruiting | Dose Finding Study of L19TNF and Doxorubicin in Patients With STS Soft Tissue Sarcoma | Phase 1 | 2019-09-05 |
| Completed | Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glio Glioma of Brain | Phase 1 / Phase 2 | 2019-05-31 |
| Unknown | Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA) Leiomyosarcoma | Phase 2 | 2018-12-27 |
| Recruiting | Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients Melanoma Stage IIIB, Melanoma Stage IIIC, Melanoma Stage IIID | Phase 3 | 2018-09-20 |
| Recruiting | A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients Wi Soft Tissue Sarcoma | Phase 3 | 2017-11-29 |
| Unknown | F16IL2 in Combination With Nivolumab in Patients With Non-small Cell Lung Cancer Non-small Cell Lung Cancer (NSCLC) | Phase 1 / Phase 2 | 2017-03-09 |
| Completed | Trial to Find and Investigate a Safe Dose of F16IL2 and BI 836858 in Patients With AML Relapse After Allogenei Acute Myeloid Leukemia (AML) Relapse | Phase 1 | 2016-12-02 |
| Active Not Recruiting | Neoadjuvant L19IL2/L19TNF- Pivotal Study Malignant Melanoma | Phase 3 | 2016-07-01 |
| Terminated | A Study of the Tumor-targeting Human F16IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Ve Acute Myeloid Leukemia, Relapsed, Adult | Phase 1 | 2016-04-13 |
| Terminated | A Randomized, Placebo-controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of F8IL10 (Dekavi Rheumatoid Arthritis | Phase 2 | 2014-10-01 |
| Terminated | F16IL2 Plus Paclitaxel in Metastatic Merkel Cell Carcinoma Merkel Cell Carcinoma | Phase 2 | 2013-10-25 |
| Terminated | A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combina Diffuse Large B-cell Lymphoma (DLBCL) | Phase 1 / Phase 2 | 2013-07-31 |
| Unknown | A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Pr Metastatic Melanoma Stage IV | Phase 1 / Phase 2 | 2013-07-31 |
| Completed | L19TNFα in Combination With Doxorubicin in Patients With Advanced Solid Tumours Advanced Solid Tumors Amenable to Anthracycline Therapy, Sarcoma, Breast Cancer, Lung Carcinomas, and Gynecological Cancer Amenable to Anthracycline Therapy | Phase 1 | 2013-01-16 |
| Completed | Intratumoral Administration of L19IL2/L19TNF Malignant Melanoma, Skin | Phase 2 | 2012-12-01 |
| Completed | Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients Rheumatoid Arthritis | Phase 1 | 2011-09-01 |
| Terminated | 131I-L19SIP Radioimmunotherapy Combined With Radiochemotherapy in Patients With Locally-advanced Non Small Cel Non Small Cell Lung Cancer | Phase 1 | 2010-05-01 |
| Completed | Intratumoral Application of L19IL2 in Patients With Malignant Melanoma Malignant Melanoma | Phase 2 | 2010-04-01 |
| Completed | 131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Bra Brain Metastases From Solid Tumors | Phase 2 | 2009-10-01 |
| Terminated | Radioimmunotherapy With 131I-L19SIP in Patients With Cancer Patients With Cancer | Phase 1 / Phase 2 | 2008-11-01 |
| Completed | Phase 1 Dose-finding Study of L19TNFα Plus Melphalan Using Isolated Inferior Limb Perfusion (ILP) in Subjects Patients With Intransit Stage III/IV Melanoma | Phase 1 | 2008-10-01 |
| Completed | A Dose Finding and Efficacy Study of the Tumour Targeting Human 131I-F16SIP Monoclonal Antibody in Patients Wi Cancer | Phase 1 / Phase 2 | 2008-09-01 |
| Completed | Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients Solid Tumor, Breast Cancer, Metastatic Melanoma | Phase 1 / Phase 2 | 2008-08-06 |
| Terminated | Clinical Study Phase II of L19IL2 in Combination With Dacarbazine in Patients With Metastatic Melanoma Metastatic Melanoma | Phase 2 | 2008-06-01 |
| Terminated | Combination Therapy of F16IL2 and Doxorubicin in Solid Tumour Patients Advanced Solid Tumor, Breast Cancer | Phase 1 / Phase 2 | 2008-06-01 |
| Completed | L19TNFα in Patients With Advanced Solid Tumors Solid Tumors, Colorectal Cancer | Phase 1 / Phase 2 | 2007-09-01 |
| Terminated | Combination Therapy of L19IL2 and Gemcitabine in Advanced Pancreatic Cancer Patients Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection | Phase 1 | 2007-06-01 |
| Completed | A Dose Finding Pharmacokinetic Study of the Tumour-targeting Human L19IL2 Monoclonal Antibody-Cytokine Fusion Advanced Solid Tumours | Phase 1 / Phase 2 | 2005-11-01 |