| Recruiting | Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT) (J-MANEUVER) Tenosynovial Giant Cell Tumor | Phase 2 | 2026-03-26 |
| Recruiting | A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participan Infertility | Phase 3 | 2026-02-05 |
| Completed | An Ethno-bridging Study of Pergoveris in Healthy Premenopausal Participants of Japanese or Caucasian Origin Fertility | Phase 1 | 2025-11-24 |
| Active Not Recruiting | Anti-CEACAM5 ADC Precemtabart Tocentecan (M9140) in Chinese Participants With Solid Tumors Solid Tumors, Colorectal Cancer | Phase 1 | 2024-12-20 |
| Recruiting | Effect of Renal Impairment on Enpatoran Pharmacokinetics Renal Impairment | Phase 1 | 2024-09-24 |
| Recruiting | Phase 1 Single Ascending Doses (SAD) of M5542 in Healthy Participants Healthy | Phase 1 | 2024-09-12 |
| Completed | A TQT Study to Investigate the Effect of Enpatoran on Cardiac Repolarization in Healthy Participants Healthy | Phase 1 | 2024-09-10 |
| Recruiting | Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With General Generalized Myasthenia Gravis | Phase 3 | 2024-06-25 |
| Active Not Recruiting | JAVEMACS: Japan AVElumab Maintenance And Continuous Treatment Study Urothelial Carcinoma | — | 2024-05-09 |
| Active Not Recruiting | Tuvusertib (M1774) Human Mass Balance and Absolute Bioavailability Study (DDRIVER Solid Tumors 303) Solid Tumor | Phase 1 | 2024-03-25 |
| Completed | Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescent Malaria Infection | Phase 2 | 2023-11-28 |
| Active Not Recruiting | Cladribine Tablets Level of Response Predictors in Clinical Practice (CLODINA) Multiple Sclerosis | — | 2023-08-03 |
| Completed | Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plas Acute Malaria | Phase 2 | 2023-03-29 |
| Completed | Concor® Bioequivalence Study in Chinese Participants (Darmstadt-Nantong) Healthy | Phase 1 | 2023-02-28 |
| Completed | Treatment Outcomes in Japanese RCC Patients Treated With Avelumab Plus Axitinib as First-line Therapy: Retrosp Renal Cell Carcinoma | — | 2023-01-25 |
| Completed | Relative Bioavailability of Evobrutinib Tablet Batches Healthy | Phase 1 | 2023-01-18 |
| Completed | A Study to Investigate the Association of Real-world Sensor-derived Biometric Data With Clinical Parameters an Pulmonary Disease, Chronic Obstructive | N/A | 2022-12-05 |
| Completed | A TQT Study of Effect of M2951 on Cardiac Repolarization Healthy | Phase 1 | 2022-11-08 |
| Completed | PK Study of Xevinapant (Debio 1143) in Healthy East Asian Participants Healthy | Phase 1 | 2022-09-26 |
| Active Not Recruiting | The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE) Systemic Lupus Erythematosus | Phase 2 | 2022-09-16 |
| Completed | Effect of Evobrutinib on Pharmacokinetics of a Combined Oral Contraceptive Healthy | Phase 1 | 2022-08-24 |
| Completed | GXR RM China BE Study (Darmstadt - Jiangsu) Healthy | Phase 1 | 2022-07-25 |
| Completed | A Study to Learn About the Study Medicine (Avelumab) in Japanese Patients With Urothelial Carcinoma That Has S Urothelial Carcinoma | — | 2022-07-19 |
| Completed | A Study to Learn About the Study Medicine (Called Avelumab) in People With Advanced Urothelial Cancer After Ch Urothelial Cancer | — | 2022-06-29 |
| Completed | Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208) Advanced Solid Tumor | Phase 1 | 2022-02-15 |
| Completed | Study Comparing Pharmacokinetics of Different Formulations of Evobrutinib in Healthy Participants Healthy | Phase 1 | 2022-02-02 |
| Completed | Tepotinib Drug-Drug Interaction Study With Itraconazole in Healthy Participants Healthy | Phase 1 | 2022-01-21 |
| Completed | DDI Study of Evobrutinib and Carbamazepine Healthy | Phase 1 | 2022-01-13 |
| Completed | BE of Euthyrox® Tablets (Merck Nantong Versus Merck Darmstadt Sites) Healthy | Phase 1 | 2022-01-10 |
| Completed | Tepotinib Drug-Drug Interaction Study With Carbamazepine in Healthy Participants Healthy | Phase 1 | 2021-12-15 |
| Completed | Enpatoran Human Mass Balance and Absolute Bioavailability Study Healthy | Phase 1 | 2021-11-05 |
| Completed | Drug-Drug Interaction Study of Evobrutinib and Transporter Substrates Healthy | Phase 1 | 2021-10-04 |
| Completed | Effectiveness of Cladribine Tablets in Participants With Highly-active Relapsing Multiple Sclerosis (CAMELOT-M Relapsing-Remitting Multiple Sclerosis | — | 2021-08-11 |
| Completed | An Observational Study to Evaluate the Efficacy and Safety of Avelumab + Axitinib Combination in Participants Carcinoma, Renal Cell | — | 2021-08-09 |
| Completed | Pergoveris FD and Liquid China BE Study Healthy | Phase 1 | 2021-05-08 |
| Completed | Study of M5049 in Healthy Japanese and Caucasian Participants Healthy | Phase 1 | 2021-05-06 |
| Completed | Extension to the MAGNIFY MS Trial on Mavenclad® (Magnify MS Extension) Multiple Sclerosis | Phase 4 | 2021-03-10 |
| Completed | Cognition and HRQoL in Adults With Highly-active RMS in Year 3 and 4 After Initial Mavenclad® Dose (CLARIFY MS Multiple Sclerosis | Phase 4 | 2021-02-23 |
| Completed | Effect of Food on Peposertib PK Healthy | Phase 1 | 2021-01-14 |
| Completed | Drug-drug Interaction Study of Evobrutinib With Midazolam in Healthy Participants Healthy | Phase 1 | 2021-01-11 |
| Completed | GXR RM (Glucophage® Extended Release Reduced Mass) 500 Milligram (mg) Korea Bioequivalence (BE) Study Healthy | Phase 1 | 2020-12-22 |
| Completed | Study of M5049 in CLE and SLE Participants Systemic Lupus Erythematosus, Cutaneous Lupus Erythematosus | Phase 1 | 2020-12-16 |
| Completed | Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK Hepatic Impairment | Phase 1 | 2020-09-30 |
| Terminated | Study of Evobrutinib in Participants With RMS (evolutionRMS 2) Relapsing Multiple Sclerosis | Phase 3 | 2020-07-02 |
| Completed | Bioequivalence Study of Coated Cesol Tablet Formulation Versus Biltricide Healthy | Phase 1 | 2020-06-17 |
| Terminated | Study of Evobrutinib in Participants With RMS (evolutionRMS 1) Relapsing Multiple Sclerosis | Phase 3 | 2020-06-12 |
| Completed | Relative Bioavailability (rBA) of Evobrutinib Intended Commercial and Clinical Tablets, and Effect of Food on Healthy | Phase 1 | 2020-05-25 |
| Completed | Chemoprophylactic Activity of M5717 in PfSPZ Challenge Model Healthy | Phase 1 | 2020-02-17 |
| Completed | Prospective Effectiveness and Safety Study of Cladribine in Participants Who Change First-line DMD Treatments Multiple Sclerosis | — | 2019-12-10 |
| Completed | A Comparative Study of New Formulation and Approved Formulation for Levothyroxine in Healthy Volunteers Healthy | Phase 1 | 2019-12-06 |
| Completed | Bioequivalence of 5 Tablets of 100 mg Versus 2 Tablets of 250 mg TF3 of Tepotinib Healthy | Phase 1 | 2019-10-17 |
| Completed | Deflox Tablets Bioequivalence (BE) Trial Healthy | Phase 1 | 2019-09-21 |
| Completed | Bioequivalence of Two Formulations of Levothyroxine Sodium 200 Micrograms (mcg) Under Tablet Form Healthy | Phase 1 | 2019-06-25 |
| Completed | Effect of Meal Composition and Timing on Evobrutinib Bioavailability Healthy | Phase 1 | 2019-04-15 |