| Completed | Phase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NS Metastatic Non-small Cell Lung Cancer, NSCLC | Phase 1 / Phase 2 | 2017-12-20 |
| Completed | A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignanc Colorectal Cancer, Ovarian Cancer, Appendiceal Cancer | Phase 1 / Phase 2 | 2017-09-07 |
| Completed | Phase 1/2 Study of Ensartinib and Durvalumab, in ALK-rearranged Non-small Cell Lung Cancer Non-small Cell Lung Cancer, Carcinoma, NSCLC | Phase 1 / Phase 2 | 2017-05-10 |
| Completed | A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers Head and Neck Squamous Cell Carcinoma, Breast Cancer, Sarcoma | Phase 1 / Phase 2 | 2016-12-28 |
| Terminated | Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant Multiple Myeloma | Phase 1 | 2016-12-13 |
| Completed | Pilot Study of the Safety/Efficacy of Combination Checkpoint Blockade + External Beam Radiotherapy in Stage IV Melanoma | Phase 1 | 2016-10-13 |
| Completed | Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer Esophageal Cancer | Phase 1 / Phase 2 | 2016-06-24 |
| Completed | Phase 1/2 Study of Motolimod, Doxorubicin, and Durvalumab in Recurrent, Platinum-Resistant Ovarian Cancer Ovarian Cancer | Phase 1 / Phase 2 | 2015-12-02 |
| Completed | Phase 2 Study of Durvalumab (MEDI4736) in Patients With Glioblastoma Glioblastoma | Phase 2 | 2015-02-26 |
| Completed | Safety and Bioimaging Trial of DS-8895a in Patients With Advanced EphA2 Positive Cancers Malignant Solid Tumor, Metastatic EphA2 Positive Cancer | Phase 1 | 2014-12-09 |
| Terminated | Phase I Study of Intralesional Bacillus Calmette-Guerin (BCG) Followed by Ipilimumab in Advanced Metastatic Me Metastatic Melanoma | Phase 1 | 2014-03-01 |
| Withdrawn | Study of the Combination of Anti-OX40 and Ipilimumab in Patients With Metastatic Melanoma Metastatic Melanoma | Phase 1 / Phase 2 | 2014-03-01 |
| Terminated | NY-ESO-1 Vaccine in Combination With Ipilimumab in Patients With Unresectable or Metastatic Melanoma Unresectable or Metastatic Melanoma | Phase 1 | 2014-01-24 |
| Completed | A Phase 1 Study to Evaluate MEDI4736 in Combination With Tremelimumab Breast Cancer, Ovarian Cancer, Colorectal Cancer | Phase 1 | 2013-12-19 |
| Withdrawn | Single Dose of Intravenous rhTNF-α and Liposomal Doxorubicin in Patients With Advanced Solid Tumors or Lymphom Solid Tumors, Lymphomas | Phase 1 | 2013-01-01 |
| Completed | MAGE-A3 Protein + AS15 as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transpla Multiple Myeloma | Phase 1 | 2011-09-01 |
| Terminated | Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer Small Cell Lung Cancer | Phase 2 | 2011-01-01 |
| Completed | A Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer Colorectal Neoplasms | Phase 1 | 2010-10-12 |
| Completed | Vaccine Therapy in Stage II, III, or IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer | Phase 1 | 2008-11-14 |
| Completed | Phase II Study of KW2871 Combined With High Dose Interferon-α2b in Patients With Metastatic Melanoma Metastatic Melanoma, Cutaneous Melanoma | Phase 2 | 2008-03-28 |
| Completed | Phase 1 Study of NY-ESO-1 Overlapping Peptides in Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Ca Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer | Phase 1 | 2008-03-01 |
| Terminated | Study of Safety and Functional Imaging of cG250 and Sunitinib in Patients With Advanced Renal Cell Carcinoma Renal Cell Carcinoma (RCC) | Phase 1 | 2008-02-01 |
| Completed | Study of ADI-PEG 20 in Patients With Advanced Melanoma Metastatic Melanoma, Skin Cancer, Neoplasm | Phase 1 / Phase 2 | 2007-07-01 |
| Completed | A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen Melanoma, Sarcoma, Gastrointestinal Stromal Tumor (GIST) | Phase 1 | 2007-05-01 |
| Completed | NY-ESO-1 Protein With Montanide and CpG 7909 as Cancer Vaccine in Several Tumors Tumors | Phase 1 | 2006-03-21 |
| Terminated | Biodistribution Study of CMD-193 in Patients With Advanced Tumours Expressing the Lewis-Y Antigen Neoplasms | Phase 1 | 2006-02-01 |
| Completed | Study of NY-ESO-1 ISCOMATRIX® in Patients With High-risk, Resected Melanoma Melanoma | Phase 2 | 2005-09-01 |
| Completed | NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting) Malignant Melanoma | Phase 1 | 2005-08-24 |
| Completed | Treatment of Patients With Advanced Renal Cancer With a Radiolabeled Antibody, Yttrium-90 Conjugated Chimeric Renal Cell Carcinoma, Kidney Neoplasm, Renal Cancer | Phase 1 | 2005-07-06 |
| Completed | Safety and Immunogenicity of CHP-HER2 and CHP-NY-ESO-1 Protein With OK-432 in Antigen-Expressing Cancers Esophageal Cancer, Lung Cancer, Stomach Cancer | Phase 1 | 2005-07-01 |
| Terminated | A Study of Anti-CTLA-4 Antibody in Patients With Advanced Synovial Sarcoma Synovial Sarcoma | Phase 2 | 2005-06-08 |
| Completed | Safety Study With the Antibody, cG250, and Isotope, 124-Iodine, to Diagnose Patients With Renal Masses. Cancer of Kidney, Kidney Cancer, Renal Cancer | Phase 1 | 2005-06-01 |
| Completed | 111In-ch806 in Patients With Advanced Tumours Expressing the 806 Antigen Neoplasms | Phase 1 | 2005-05-01 |
| Completed | Phase I Trial of huA33 Plus Chemotherapy in Patients With Metastatic Colorectal Cancer Colorectal Cancer | Phase 1 | 2005-04-18 |
| Completed | Phase I/II Dose-escalation Study of Lutetium-177-labeled cG250 in Patients With Advanced Renal Cancer Metastatic Renal Cell Carcinoma | Phase 1 / Phase 2 | 2005-02-01 |
| Terminated | Immunization With the MAGE-3.A1 Peptide Mixed With the Adjuvant CpG 7909 in Patients With Metastatic Melanoma Malignant Melanoma | Phase 1 / Phase 2 | 2005-01-12 |
| Terminated | Immunization With 8 Peptides Mixed With CpG 7909 or Montanide ISA51 in Patients With Metastatic Cutaneous Mela Malignant Melanoma | Phase 1 / Phase 2 | 2005-01-01 |
| Completed | Vaccine Therapy in Patients With Stage II, III, or IV Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer | Phase 2 | 2004-12-01 |
| Completed | Immunization With NY-ESO-1 Protein Combined With CpG 7909 in Patients With Prostate Cancer Prostate Cancer | Phase 1 | 2004-10-27 |
| Completed | NY-ESO-1 Plasmid DNA (pPJV7611) Cancer Vaccine Prostate Cancer, Bladder Cancer, Non-small Cell Lung Cancer | Phase 1 | 2004-09-27 |
| Completed | Monoclonal Antibody Therapy in Treating Patients With Progressive Small Cell Lung Cancer (SCLC) Lung Cancer | Phase 1 | 2004-07-26 |
| Completed | Safety Study of NY-ESO-1 Protein Vaccine to Treat Cancer Expressing NY-ESO-1 Neoplasms | Phase 1 | 2004-06-01 |
| Completed | Study of NY-ESO-1 ISCOMATRIX® in Patients With Measurable Stage III or IV Melanoma Melanoma | Phase 2 | 2003-11-28 |
| Completed | Radiolabeled Monoclonal Antibody in Treating Patients With Advanced Ovarian Epithelial Cancer Ovarian Cancer | Phase 1 | 2003-11-01 |
| Completed | Vaccine Therapy in Treating Patients With Transitional Cell Carcinomas Transitional Cell Carcinoma | Phase 1 | 2003-10-28 |
| Completed | Capecitabine and 131I-huA33 in Patients With Metastatic Colorectal Cancer Colorectal Neoplasms | Phase 1 | 2003-10-01 |
| Completed | A Pilot Study of NY-ESO-1b Peptide Plus CpG 7909 and Montanide® ISA-51 in Patients With Cancer. Cancer, Neoplasm | Phase 1 | 2003-09-03 |
| Completed | Vaccine Therapy in Treating Patients With Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer | Phase 1 | 2003-06-23 |
| Terminated | Monoclonal Antibody Therapy in Treating Patients Scheduled for Surgery to Remove Ovarian Cancer Ovarian Cancer | Phase 1 | 2000-08-02 |
| Terminated | Monoclonal Antibody Therapy in Treating Patients With Advanced Colorectal Cancer Colorectal Cancer | Phase 1 | 2000-07-12 |
| Completed | Monoclonal Antibody Therapy in Treating Patients With Advanced Kidney Cancer Kidney Cancer | Phase 1 / Phase 2 | 1998-11-17 |