| Terminated | Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholi Biliary Atresia | Phase 2 / Phase 3 | 2024-09-02 |
| Terminated | To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate Primary Biliary Cholangitis | Phase 3 | 2024-07-01 |
| Recruiting | FXR Effect on Severe Alcohol-Associated Hepatitis (FRESH) Study Alcohol Associated Hepatitis | Phase 2 | 2022-12-15 |
| Withdrawn | A Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients Primary Biliary Cholangitis | — | 2022-03-28 |
| Completed | Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC Primary Biliary Cholangitis | Phase 2 | 2022-03-21 |
| Terminated | Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC Primary Biliary Cholangitis | Phase 2 | 2019-10-02 |
| Terminated | Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Ch Liver Cirrhosis, Biliary | Phase 4 | 2018-06-22 |
| Completed | Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Non Compensated Cirrhosis, Nonalcoholic Steatohepatitis | Phase 3 | 2017-08-30 |
| Completed | Combination Obeticholic Acid (OCA) and Statins for Monitoring of Lipids (CONTROL) Nonalcoholic Steatohepatitis | Phase 2 | 2015-12-04 |
| Terminated | Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment Non Alcoholic Steatohepatitis (NASH) | Phase 3 | 2015-09-22 |
| Terminated | Obeticholic Acid in Pediatric Subjects With Biliary Atresia Biliary Atresia | Phase 2 | 2015-07-01 |
| Completed | Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients Primary Biliary Cholangitis | — | 2015-06-01 |
| Completed | Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC) Primary Sclerosing Cholangitis (PSC) | Phase 2 | 2015-02-09 |
| Terminated | Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis Liver Cirrhosis, Biliary | Phase 4 | 2014-12-26 |
| Completed | Phase 2 Study on Effects of Obeticholic Acid (OCA) on Lipoprotein Metabolism in Participants With Primary Bili Primary Biliary Cirrhosis | Phase 2 | 2013-12-03 |
| Completed | Single Dose and Multiple Dose Trial to Assess Pharmacokinetics of Obeticholic Acid (OCA) Healthy | Phase 1 | 2013-10-01 |
| Completed | Effect of Food on Pharmacokinetics of Obeticholic Acid (OCA) Healthy | Phase 1 | 2013-08-01 |
| Completed | Hepatic Impairment Trial of Obeticholic Acid Hepatic Impairment | Phase 1 | 2013-06-01 |
| Completed | Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis Primary Biliary Cirrhosis | Phase 3 | 2012-01-01 |
| Completed | Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC) Liver Cirrhosis, Biliary | Phase 2 | 2008-01-17 |
| Terminated | Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC) Liver Cirrhosis, Biliary | Phase 2 | 2007-10-01 |
| Completed | Study of INT-747 in Patients With Diabetes and Presumed NAFLD Diabetes Mellitus, Type II, Fatty Liver | Phase 2 | 2007-07-01 |