| Active Not Recruiting | HMPL-523 (Sovleplenib) in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia Warm Antibody Autoimmune Hemolytic Anemia | Phase 2 / Phase 3 | 2022-09-30 |
| Completed | Surufatinib Plus Anti-PD-1/L1 as Maintenance Therapy in Extensive-Stage Small Cell Lung Cancer Extensive-Stage Small Cell Lung Cancer | Phase 2 | 2022-09-27 |
| Completed | A Clinical Study to Evaluate the Pharmacokinetics and Bioequivalence of HMPL-523 Tablets Produced by Two Diffe Healthy Subject | EARLY_Phase 1 | 2022-06-01 |
| Unknown | HMPL-453 (FGFR Inhibitor) in Combination With Chemotherapy or Anti-PD-1 Antibody in Advanced Solid Tumors Solid Tumor | Phase 1 / Phase 2 | 2022-01-22 |
| Unknown | Clinical Study of HMPL-653 in Treatment of Advanced Malignant Solid Tumors and TGCT Advanced Malignant Solid Tumors, TGCT | Phase 1 | 2022-01-18 |
| Active Not Recruiting | Study on Savolitinib Combined With Osimertinib in Treatment of Advanced NSCLC With MET Amplification Non-small Cell Lung Cancer | Phase 3 | 2021-11-22 |
| Active Not Recruiting | Phase III Study on HMPL-523 for Treatment of ITP Primary Immune Thrombocytopenia (ITP) | Phase 3 | 2021-10-27 |
| Unknown | A Phase 3 Study to Evaluate Surufatinib Plus Toripalimab in the Treatment of Advanced Neuroendocrine Carcinoma Advanced Neuroendocrine Carcinoma | Phase 3 | 2021-09-18 |
| Active Not Recruiting | Clinical Study on Savolitinib + Osimertinib in Treatment of EGFRm+/MET+ Locally Advanced or Metastatic NSCLC Non-small Cell Lung Cancer | Phase 3 | 2021-09-06 |
| Completed | Savolitinib for Treating Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Patients Non-small Cell Lung Cancer Metastatic | Phase 3 | 2021-08-19 |
| Active Not Recruiting | Savolitinib for Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients Gastric Cancer, Esophagogastric Junction Disorder | Phase 2 | 2021-07-27 |
| Completed | Clinical Study of HMPL-689 for Relapsed/Refractory Marginal Zone Lymphoma and Follicular Lymphoma Marginal Zone Lymphoma, Follicular Lymphoma | Phase 2 | 2021-04-15 |
| Completed | Surufatinib Renal Impairment Study Renal Impairment | Phase 1 | 2021-02-12 |
| Completed | Surufatinib Hepatic Impairment Study Hepatic Impairment | Phase 1 | 2021-02-12 |
| Completed | Fruquintinib Food Effect and Proton Pump Inhibitor Study Drug Interaction, Food-drug Interaction | Phase 1 | 2020-09-24 |
| Completed | Fruquintinib CYP3A Inhibitor and Inducer Study Drug Drug Interaction | Phase 1 | 2020-09-02 |
| Completed | A Study to Assess the Effect of a High Fat Meal on Surufatinib in Healthy Subjects Healthy | Phase 1 | 2020-08-14 |
| Completed | A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer Metastatic Colorectal Cancer, Metastatic Colon Cancer | Phase 3 | 2020-08-12 |
| Completed | Surufatinib DDI With a PPI and a CYP3A Inducer Healthy | Phase 1 | 2020-07-09 |
| Completed | A Study to Assess the Effect of a Strong CYP3A Inhibitor, on Surufatinib in Healthy Subjects Healthy | Phase 1 | 2020-07-09 |
| Unknown | A Study of HMPL-306 in Patients With IDH1 and/or IDH2 Mutation of Relapsed/Refractory Myeloid Leukemia/Neoplas Acute Myeloid Leukemia | Phase 1 | 2020-05-14 |
| Unknown | HMPL-453 in Advanced Malignant Mesothelioma Advanced Malignant Mesothelioma | Phase 2 | 2019-12-30 |
| Completed | Study of Surufatinib Single Agent or Surufatinib Combined With Toripalimab in Patients With Advanced Solid Tum Advanced Solid Tumors | Phase 2 | 2019-12-26 |
| Completed | The Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-523 in Immune Thrombocytopenia Pat Immune Thrombocytopenia (ITP) | Phase 1 | 2019-08-12 |
| Completed | A Pharmacokinetic and Bioequivalence Study of Savolitinib Tablets in Healthy Chinese Male Volunteers Bioequivalence | Phase 1 | 2019-04-16 |
| Terminated | Phase I Study of HMPL-523+Azacitidine in Elderly Patients With Acute Myeloid Leukemia Acute Myeloid Leukemia | Phase 1 | 2018-10-09 |
| Unknown | A Trial Evaluating Surufatinib Efficacy and Safety in Biliary Tract Carcinoma Patients Biliary Tract Cancer | Phase 2 / Phase 3 | 2018-07-10 |
| Withdrawn | Study of Fruquintinib (HMPL-013) in High Risk Patients With Advanced NSCLC Lung Cancer | Phase 2 | 2018-05-08 |
| Completed | To Explore the Pharmacokinetics and Relative Bioavailability of Sulfatinib Capsules in Two Different Manufactu Relative Bioavailability | Phase 1 | 2018-04-02 |
| Completed | A Mass Balance Study to Investigate the Absorption, Metabolism, and Excretion of [14C]Sulfatinib Healthy | EARLY_Phase 1 | 2018-04-02 |
| Unknown | HMPL-813 in Treating Patients With Glioblastoma Glioblastoma | Phase 1 | 2018-01-26 |
| Completed | A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers Advanced Solid Tumors, Metastatic Colon Cancer, Metastatic Breast Cancer | Phase 1 | 2017-12-11 |
| Completed | A Phase III Study of Fruquintinib in Combination With Paclitaxel in Second Line Gastric Cancer(FRUTIGA) Advanced Gastric Cancer | Phase 3 | 2017-10-18 |
| Completed | A Study of HMPL-689 in Patients With Lymphomas Failed of Standard of Care or no Standard of Care Existed Lymphomas | Phase 1 | 2017-08-08 |
| Unknown | A Study of HMPL-453 in Patients With Advanced Solid Malignancies Solid Tumor, Adult | Phase 1 / Phase 2 | 2017-05-23 |
| Completed | Study of Surufatinib as Second-line Treatment in Patients With Biliary Tract Carcinoma Biliary Tract Cancer | Phase 2 | 2017-01-03 |
| Terminated | A Dose Escalation Study to Assess the Safety and Tolerability of HMPL-453 in Patients With Advanced Solid Mali Solid Tumor | Phase 1 | 2017-01-01 |
| Completed | A Study of Hutchison MediPharma Limited(HMPL)-523 in Patients With Relapsed or Refractory Mature B-cell Neopla Mature B-cell Neoplasms | Phase 1 | 2016-12-27 |
| Completed | A Phase II Study of Fruquintinib in Combination With Gefitinib in Patients With Advanced Non-small Cell Lung C NSCLC | Phase 2 | 2016-12-01 |
| Unknown | A Phase II Study of HMPL-504 in Lung Sarcomatoid Carcinoma and Other Non-small Cell Lung Cancer Lung Sarcomatoid Carcinoma | Phase 2 | 2016-12-01 |
| Completed | A Mass Balance Study to Investigate the Absorption, Metabolism, and Excretion Of [14C] Fruquintinib Healthy | Phase 1 | 2016-07-01 |
| Completed | A Study of HMPL-689 in Healthy Volunteers Healthy Volunteers | Phase 1 | 2016-03-23 |
| Completed | Study of Sulfatinib in Treating Advanced Medullary Thyroid Carcinoma and Iodine-refractory Differentiated Thyr Thyroid Carcinoma | Phase 2 | 2016-02-24 |
| Completed | A Phase III Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer NSCLC | Phase 3 | 2015-12-09 |
| Completed | Phase III Study of Surufatinib in Treating Advanced Pancreatic Neuroendocrine Tumors Neuroendocrine Tumors | Phase 3 | 2015-12-07 |
| Completed | Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors Neuroendocrine Tumors | Phase 3 | 2015-12-07 |
| Unknown | A Study of HMPL-523 in Relapsed or Refractory Hematologic Malignancies Hematologic Malignancies | Phase 1 | 2015-11-01 |
| Terminated | Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor Cancer | Phase 1 | 2015-04-01 |
| Completed | A Phase I Study of Safety and Pharmacokinetics of Volitinib in Combination With Gefitinib in EGFR(+) NSCLC Non-Small Cell Lung Cancer | Phase 1 | 2015-04-01 |
| Completed | A Phase III Trial Evaluating Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients （FRESCO) Colorectal Cancer | Phase 3 | 2014-12-01 |
| Completed | A Food Effect Phase I Study of the Sulfatinib in Healthy Subjects (HMPL-012) Healthy | Phase 1 | 2014-12-01 |
| Completed | A Phase Ib/2 Clinical Study of Fruquintinib Combined With Paclitaxel in the Treatment of Advanced Gastric Canc Gastric Cancer | Phase 1 / Phase 2 | 2014-11-09 |
| Completed | Phase Ib/II Study of Sulfatinib in Treating Advanced Neuroendocrine Tumors Neuroendocrine Tumors | Phase 1 | 2014-10-31 |
| Completed | A Study of Safety and Pharmacokinetics of Volitinib With Docetaxel in Patients With Advanced Gastric Cancer Gastric Cancer | Phase 1 | 2014-09-01 |
| Completed | A Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer Non-small Cell Lung Cancer | Phase 2 | 2014-05-29 |
| Completed | A Study of the Safety, Tolerability and Pharmacokinetics of HMPL-523 Rheumatoid Arthritis (RA) | Phase 1 | 2014-05-01 |
| Completed | Study of Fruquintinib in Patients With Metastatic Colorectal Cancer Colorectal Cancer | Phase 2 | 2014-04-01 |
| Completed | A Food Effect Phase I Study of the Volitinib in Healthy Subjects Food Effect, Health Subjects | Phase 1 | 2013-11-01 |
| Terminated | HMPL-004 Maintenance Treatment in Subjects With Mild to Moderate Ulcerative Colitis Ulcerative Colitis | Phase 3 | 2013-06-01 |
| Completed | Phase I Study of the Volitinib (HMPL-504) in Patients With Advanced Solid Tumors Tumors | Phase 1 | 2013-05-01 |
| Terminated | A Phase III Trial of HMPL-004 in Patients With Mild to Moderate Active Ulcerative Colitis Ulcerative Colitis | Phase 3 | 2013-03-01 |
| Completed | A Phase Ib Study of Fruquintinib in 3rd Line mCRC Colorectal Cancer | Phase 1 / Phase 2 | 2012-12-01 |
| Completed | Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor Cancer | Phase 1 | 2012-10-01 |
| Completed | Food Effect Study of Single Dose of Fruquintinib (HMPL-013) in Healthy Subjects Food Effect of Fruquintinib in Health Subjects | Phase 1 | 2012-06-01 |
| Completed | Phase I Study of the Volitinib (HMPL-504) in Patients With Advanced Solid Tumors Tumor | Phase 1 | 2012-02-01 |
| Completed | A Phase I Study of Epitinib(HMPL-813) in Patients With Advanced Solid Tumors Solid Tumor | Phase 1 | 2011-10-31 |
| Completed | Phase I Clinical Trial in Healthy Male Volunteers Inflammatory Bowel Diseases | Phase 1 | 2011-09-01 |
| Completed | Phase I Study of Fruquintinib(HMPL-013) in Patients With Advanced Solid Tumors Tumor | Phase 1 | 2011-01-01 |
| Completed | Phase I Study of Sulfatinib(HMPL-012) in Patients With Advanced Solid Tumors Tumor | Phase 1 | 2010-04-01 |
| Completed | Phase II Study of HMPL-004 in Patients With Ulcerative Colitis Ulcerative Colitis | Phase 2 | 2008-02-07 |
| Completed | Phase II Study of HMPL-004 in Subjects With Crohn's Disease Crohn's Disease | Phase 2 | 2006-04-01 |