| Active Not Recruiting | Phase 2 Trial Assessing TBAJ876 or Bedaquiline, with Pretomanid and Linezolid in Adults with Drug-sensitive Pu Pulmonary TB, Pulmonary Tuberculosis, Drug Sensitive Tuberculosis | Phase 2 | 2023-10-24 |
| Completed | A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults Pulmonary Disease, Tuberculosis, Pulmonary, Tuberculosis | Phase 1 | 2022-06-30 |
| Completed | A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant, Tuberculosis, MDR | Phase 2 | 2021-09-16 |
| Completed | Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects Tuberculosis, Tuberculosis, Pulmonary | Phase 1 | 2021-02-03 |
| Completed | Evaluation of the Safety, Tolerability, PK of TBAJ-587 in Healthy Adults Tuberculosis | Phase 1 | 2020-12-01 |
| Completed | Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults Pulmonary Disease, Tuberculosis, Pulmonary, Tuberculosis | Phase 1 | 2020-06-08 |
| Completed | Single-dose Study in Two Panels of Healthy Adult Participants to Assess Immediate-Release and Dispersible Form Multi-drug Resistant Tuberculosis | Phase 1 | 2020-01-14 |
| Completed | A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults Tuberculosis, Tuberculosis, Pulmonary | Phase 1 | 2019-01-16 |
| Completed | Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant, Tuberculosis, MDR | Phase 2 / Phase 3 | 2018-07-30 |
| Completed | Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tub Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant, Tuberculosis, MDR | Phase 3 | 2017-11-21 |
| Completed | Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid Tuberculosis, Tuberculosis, Pulmonary | Phase 1 | 2017-09-26 |
| Completed | A Phase 1 Study to Evaluate Safety, Tolerability, PK, and PK Interactions of TBA-7371 Tuberculosis, Tuberculosis, Pulmonary | Phase 1 | 2017-08-29 |
| Terminated | A Multiple Ascending Dose Study With a Dose Formulation Comparison Cohort to Evaluate the Safety, Tolerability Tuberculosis | Phase 1 | 2015-11-01 |
| Completed | A Phase 3 Trial Assessing Safety and Efficacy of B-Pa-L in Participants With DR-TB Pulmonary Tuberculosis | Phase 3 | 2015-03-01 |
| Completed | Shortening Treatment by Advancing Novel Drugs Tuberculosis, Pulmonary, Drug Sensitive, Tuberculosis, Pulmonary, Multi Drug-resistant | Phase 3 | 2015-02-01 |
| Completed | A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subject Tuberculosis | Phase 1 | 2015-01-01 |
| Completed | A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001) Pulmonary Tuberculosis | Phase 2 | 2014-11-01 |
| Completed | A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-8 Tuberculosis | Phase 2 | 2014-10-23 |
| Completed | Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa Pulmonary Tuberculosis | Phase 2 | 2012-10-01 |
| Completed | Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients W Pulmonary Tuberculosis | Phase 2 | 2012-03-01 |
| Completed | Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001) Pulmonary Tuberculosis | Phase 2 | 2010-10-01 |
| Completed | Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (TMC207-CL001) Pulmonary Tuberculosis | Phase 2 | 2010-04-01 |
| Completed | PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002 Tuberculosis | Phase 1 | 2010-03-01 |
| Completed | Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam Tuberculosis | Phase 1 | 2009-12-01 |
| Completed | Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009) Tuberculosis | Phase 1 | 2009-09-01 |
| Completed | Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010) Pulmonary Tuberculosis | Phase 2 | 2009-08-01 |
| Completed | Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary Tuberculosis Pulmonary Tuberculosis | Phase 3 | 2008-01-01 |
| Completed | PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis Pulmonary Tuberculosis | Phase 2 | 2007-08-01 |
| Completed | Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects Tuberculosis | Phase 1 | 2007-03-01 |
| Completed | A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Tuberculosis | Phase 1 | 2006-03-01 |