| Recruiting | Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age Prevention of Pneumonic Plague Resulting From Aerosol Exposure to Yersenia Pestis | Phase 2 | 2025-09-11 |
| Recruiting | Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Health Shingles, Herpes Zoster, Vaccine-Preventable Diseases | Phase 1 / Phase 2 | 2024-06-17 |
| Completed | Trial of the Immunogenicity, Safety, and Tolerability of rF1V Vaccine With CpG 1018® Adjuvant Compared With rF Plague, Pneumonic, Plague, Vaccine-Preventable Diseases | Phase 2 | 2022-08-09 |
| Completed | Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z- Shingles, Herpes Zoster, Vaccine-Preventable Diseases | Phase 1 | 2022-01-10 |
| Unknown | DV2-HBV-27: Observational Pregnancy Registry Pregnant | — | 2021-02-21 |
| Completed | HEPLISAV-B® in Adults With End-Stage Renal Disease (ESRD) Undergoing Hemodialysis End Stage Renal Disease on Hemodialysis (Diagnosis) | Phase 1 | 2019-04-22 |
| Completed | Phase 1b DV281 With an Anti-PD-1 Inhibitor in NSCLC Advanced Non Small Cell Lung Cancer | Phase 1 | 2017-09-20 |
| Terminated | A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Mel Metastatic Melanoma, Head Neck Cancer | Phase 1 / Phase 2 | 2015-09-01 |
| Terminated | Study of SD-101 in Combination With Localized Low-dose Radiation in Patients With Untreated Low-grade B-cell L B-cell Lymphoma | Phase 1 / Phase 2 | 2014-10-01 |
| Completed | Safety and Immunogenicity Study of the Hepatitis B Vaccine, HEPLISAV™, Compared to Engerix-B® Vaccine Healthy | Phase 3 | 2014-04-01 |
| Completed | A Study of the Immune Response to Heplisav in Healthy Older Adults Hepatitis B | Phase 1 | 2013-11-01 |
| Completed | Long-Term Study on Safety and Immunogenicity of HEPLISAV™ and Engerix-B® in Adults With Chronic Kidney Disease Chronic Kidney Disease | — | 2010-12-01 |
| Completed | Safety and Immunogenicity of HEPLISAV™ a Hepatitis B Virus Vaccine in Adults on Hemodialysis End Stage Renal Disease | Phase 3 | 2010-12-01 |
| Completed | Safety and Immunogenicity Study of the Hepatitis B Virus (HBV) Vaccine, HEPLISAV Compared to Engerix-B Vaccine Healthy | Phase 3 | 2010-02-01 |
| Completed | A Study to Assess DV-601 in Subjects With Chronic Hepatitis B Hepatitis B, Chronic | Phase 1 | 2009-09-01 |
| Completed | Comparing Safety and Immunogenicity of HEPLISAV-B® to Engerix-B® in Chronic Kidney Disease (CKD) Patients Chronic Kidney Disease | Phase 3 | 2009-09-01 |
| Completed | Safety Study of SD-101 (a Novel C Type Toll-like Receptor 9 (TLR9) Agonist) for the Treatment of Chronic Hepat Chronic Hepatitis C | Phase 1 | 2008-10-01 |
| Completed | Safety, Pharmacokinetics, and Pharmacodynamics of SD-101 in Healthy Normal Males Healthy | Phase 1 | 2008-01-01 |
| Completed | An Evaluation of the Efficacy and Safety of TOLAMBA™ for Ragweed-Allergic Rhinitis in an Environmental Exposur Rhinitis, Allergic, Seasonal | Phase 2 | 2007-09-01 |
| Terminated | A Safety and Efficacy Study of a Single or Double Dose of HEPLISAV™ Hepatitis B Vaccine in Adults With End-Sta Hepatitis B | Phase 2 | 2007-07-01 |
| Completed | Open-Label Study of the Safety and Immunogenicity of HEPLISAV™ Hepatitis B Virus Vaccine Hepatitis B | Phase 2 | 2007-06-01 |
| Completed | Safety and Efficacy of HEPLISAV™ Hepatitis B Virus Vaccine Compared With Engerix-B® Vaccine Hepatitis B | Phase 3 | 2006-12-01 |
| Terminated | A Study of 1018 Immunostimulatory Sequence (ISS) Administered With Irinotecan and Cetuximab to Treat Patients Colorectal Neoplasms | Phase 1 | 2006-11-01 |
| Terminated | Efficacy and Safety Study of TOLAMBA™ in Ragweed-Allergic Adults Rhinitis, Allergic, Seasonal | Phase 2 | 2006-04-01 |
| Completed | Safety of HEPLISAV™ Hepatitis B Virus Vaccine in End-stage Kidney Failure Patients Hepatitis B | Phase 1 | 2006-01-01 |