| Completed | Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Ethinyl Estradiol/Levonorgestrel (EE/LNG) Healthy Volunteer Study | Phase 1 | 2025-12-04 |
| Recruiting | C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV HEPATITIS C VIRUS CHRONIC INFECTION, Hepatitis C, Chronic, Hepatitis C Virus Infection | Phase 3 | 2025-06-02 |
| Completed | Drug-drug Interaction Study of Omeprazole and Bemnifosbuvir/Ruzasvir Healthy Volunteer Study | Phase 1 | 2025-05-09 |
| Recruiting | Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal Healthy Volunteer Study, Hepatic Impairment, Renal Impairment | Phase 1 | 2025-04-09 |
| Completed | Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Digoxin and Rosuvastatin Healthy Volunteer Study | Phase 1 | 2025-04-08 |
| Active Not Recruiting | C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV HEPATITIS C VIRUS CHRONIC INFECTION | Phase 3 | 2025-04-07 |
| Recruiting | Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone Healthy Volunteer Study | Phase 1 | 2025-01-07 |
| Completed | Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir Healthy Volunteer Study | Phase 1 | 2024-04-15 |
| Completed | Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and Ruzasvir Healthy Volunteer Study | Phase 1 | 2023-12-14 |
| Completed | A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV Chronic Hepatitis C Virus, Hepatitis C, Chronic, Hepatitis C | Phase 2 | 2023-05-30 |
| Completed | The Study of Bemnifosbuvir in Healthy Japanese Subjects Healthy Volunteer Study | Phase 1 | 2023-04-26 |
| Completed | Study of Bemnifosbuvir on Cardiac Repolarization in Healthy Subjects Healthy Volunteer Study | Phase 1 | 2023-04-25 |
| Completed | Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function Healthy Volunteer, Hepatic Impairment | Phase 1 | 2023-01-30 |
| Completed | Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir Healthy Volunteer Study | Phase 1 | 2023-01-30 |
| Completed | SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2 Infection), COVID-19 | Phase 3 | 2022-11-25 |
| Completed | Study of AT-527 in Subjects With Normal and Impaired Renal Function Healthy Volunteer, Renal Impairment | Phase 1 | 2022-10-17 |
| Terminated | Study of AT-752 in Patients With Dengue Infection Dengue Fever | Phase 2 | 2022-04-29 |
| Terminated | Study of AT-752 in Healthy Subjects in a Dengue Human Challenge Model Dengue | Phase 1 | 2022-04-22 |
| Completed | Study of AT-527 in Healthy Subjects Under Fasting Conditions or With a Meal Healthy Volunteer Study | Phase 1 | 2022-02-22 |
| Completed | Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998) Healthy Volunteer Study | Phase 1 | 2021-11-16 |
| Completed | Drug-drug Interaction Study of Digoxin and AT-527 (R07496998) Healthy Volunteers Study | Phase 1 | 2021-11-03 |
| Withdrawn | Study of AT-777 in Healthy Subjects and AT-777 in Combination With AT-527 in HCV-Infected Subjects Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C | Phase 1 / Phase 2 | 2021-10-01 |
| Completed | Mass Balance Study of AT-527 in Healthy Adult Male Subjects (R07496998) Healthy Volunteer Study | Phase 1 | 2021-07-28 |
| Completed | Bronchopulmonary PK of AT-527 (R07496998) Healthy Volunteer Study | Phase 1 | 2021-04-25 |
| Completed | Drug-drug Interaction Study of Midazolam and AT-527 (R07496998) Healthy Volunteer Study | Phase 1 | 2021-04-22 |
| Completed | Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998) Healthy Volunteer Study | Phase 1 | 2021-04-18 |
| Completed | Study of AT-752 in Healthy Subjects Dengue | Phase 1 | 2021-03-09 |
| Completed | Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527 Healthy Volunteer Study | Phase 1 | 2021-03-01 |
| Completed | Study of AT-527 in Healthy Subjects (R07496998) Healthy Volunteer Study | Phase 1 | 2020-11-02 |
| Terminated | Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital Setting COVID-19 | Phase 2 | 2020-05-26 |
| Completed | Study of AT-527 in Combination With Daclatasvir in Subjects With Hepatitis C Virus (HCV) Infection Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C | Phase 2 | 2019-06-20 |
| Completed | Study of AT-527 in Healthy and HCV-Infected Subjects Chronic Hepatitis C, Hepatitis C, Hepatitis C, Chronic | Phase 1 | 2017-07-06 |