| Completed | Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Expr Gynecologic Cancer, Colorectal Cancer, Pancreatic Cancer | — | 2023-03-01 |
| Terminated | Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors Gynecologic Cancer, Colorectal Cancer, Pancreatic Cancer | Phase 1 / Phase 2 | 2022-04-04 |
| Terminated | HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With S Ovarian Cancer, Endometrial Cancer, Colo-rectal Cancer | — | 2021-09-24 |
| Terminated | Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Gl Glioblastoma | Phase 2 | 2019-08-01 |
| Completed | Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to Glioblastoma | Phase 1 | 2018-09-05 |
| Completed | A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substud Glioblastoma | Phase 1 | 2018-06-18 |
| Terminated | A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG Pediatric Brain Tumor, Diffuse Intrinsic Pontine Glioma | Phase 1 / Phase 2 | 2017-09-26 |
| Terminated | A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer Metastatic Breast Cancer | Phase 1 / Phase 2 | 2015-07-18 |
| Completed | A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma Glioblastoma Multiforme, Anaplastic Oligoastrocytoma | Phase 1 | 2015-06-01 |
| Terminated | Adenoviral Vector Monotherapy or Combination With Chemotherapy in Subjects With Recurrent/Metastatic Breast Ca Breast Cancer Nos Metastatic Recurrent | Phase 2 | 2013-04-04 |
| Unknown | Study of Palifosfamide-tris in Combination With Carboplatin and Etoposide in Chemotherapy Naïve Patients With Extensive-Stage Small Cell Lung Cancer | Phase 3 | 2012-05-01 |
| Completed | Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat M Melanoma | Phase 1 / Phase 2 | 2011-08-01 |
| Unknown | Effect on QTc, Pharmacokinetics, Safety, and Preliminary Efficacy of Single-agent Palifosfamide-tris in Subjec Advanced Solid Tumors | Phase 1 | 2011-06-01 |
| Unknown | Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies Malignancy, Cancer, Non Small Cell Lung Cancer | Phase 1 | 2010-11-01 |
| Completed | Study of Palifosfamide-tris in Combination With Doxorubicin in Patients With Front-line Metastatic Soft Tissue Soft Tissue Sarcoma | Phase 3 | 2010-07-01 |
| Completed | Study of Oral Darinaparsin in Patients With Advanced Solid Tumors Advanced Solid Tumors | Phase 1 | 2010-06-01 |
| Withdrawn | Safety Study of Darinaparsin in Combination With Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (C Lymphoma | Phase 1 | 2010-06-01 |
| Unknown | Study of a Novel Indibulin Dosing Schedule for the Treatment of Metastatic Breast Cancer Metastatic Breast Cancer | Phase 1 / Phase 2 | 2010-03-01 |
| Completed | Trial of an Intratumoral Injections of INXN-3001 in Subjects With Stage III or IV Melanoma Melanoma | Phase 1 | 2009-04-01 |
| Unknown | A Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Unresectable or Metastatic Soft-tissue Sa Soft Tissue Sarcoma | Phase 2 | 2008-08-01 |
| Unknown | Phase 1b Study of Indibulin in Combination With Capecitabine in Advanced Solid Tumors Advanced Solid Tumors | Phase 1 / Phase 2 | 2008-06-01 |
| Suspended | Study of Oral Palifosfamide Tris in Solid Tumors Advanced Cancer | Phase 1 | 2008-03-01 |
| Completed | Phase 1 Study of ZIO-201-T in Combination With Doxorubicin in Solid Tumors Advanced Cancer | Phase 1 | 2008-01-01 |
| Unknown | Phase I Study of Indibulin in Combination With Erlotinib in Advanced Solid Tumors Advanced Solid Tumors | Phase 1 | 2008-01-01 |
| Unknown | Phase I Study of Oral ZIO-101-C in Advanced Solid Tumors and Lymphomas Advanced Solid Tumors, Lymphomas | Phase 1 | 2007-12-01 |
| Completed | Phase IB Study of Indibulin Using Positron-Emission Tomography (PET) Scans Advanced Cancer | Phase 1 | 2007-10-01 |
| Unknown | Phase I Study of Oral Darinaparsin (ZIO-101-C)in Advanced Solid Tumors and Non-Hodgkin's Lymphomas Advanced Cancer | Phase 1 | 2007-08-01 |
| Unknown | Phase I Study in Advanced Solid Tumors Solid Tumors | Phase 1 | 2007-06-01 |
| Unknown | A Phase-II Trial of ZIO 101 in Advanced Hepatocellular Carcinoma HEPATOCELLULAR CARCINOMA | Phase 2 | 2007-01-01 |
| Unknown | A Phase II Trial of ZIO-101 in Advanced Multiple Myeloma: Protocol SGL2001b Multiple Myeloma | Phase 2 | 2007-01-01 |
| Completed | Phase II Study of ZIO-101 in Advanced Blood and Bone Marrow Cancers Hematologic Neoplasms, Bone Marrow Neoplasms, Non-Hodgkin's Lymphoma | Phase 2 | 2006-12-01 |
| Completed | Study of ZIO-201 in Advanced Sarcoma Advanced Sarcoma | Phase 1 / Phase 2 | 2006-02-01 |
| Completed | A Protocol for the Safety and Tolerance of Intravenous Isophosphoramide Mustard (IPM) in Patients With Advance Advanced Cancer | Phase 1 | 2006-02-01 |
| Completed | Study of ZIO-101 in Multiple Myeloma Multiple Myeloma | Phase 1 / Phase 2 | 2006-01-01 |
| Completed | A Phase I Trial of ZIO-101 in Solid Tumors Solid Tumors | Phase 1 | 2005-07-01 |
| Completed | A Phase I Trial of ZIO-101 in Hematologic Cancers Acute Leukemia, Chronic Myeloproliferative Disease, Chronic Lymphoproliferative Disease | Phase 1 | 2005-05-01 |
| Completed | Phase I Study of Indibulin in Patients With Solid Tumors Solid Tumors | Phase 1 | 2003-04-01 |