| Recruiting | SAD and MAD Study of AKB-9090 in Healthy Adult Participants Healthy Volunteers | Phase 1 | 2026-03-16 |
| Recruiting | A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS) Focal Segmental Glomerulosclerosis | Phase 2 | 2025-12-03 |
| Active Not Recruiting | To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients W Anemia of Chronic Kidney Disease | Phase 3 | 2025-07-24 |
| Withdrawn | Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Anemia of Chronic Kidney Disease | Phase 3 | 2025-01-01 |
| Withdrawn | Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Anemia of Chronic Kidney Disease | Phase 3 | 2025-01-01 |
| Completed | Study Evaluating the Efficacy and Safety of Dose Conversion From a Long-acting Erythropoiesis-stimulating Agen Anemia Associated With Chronic Kidney Disease (CKD) | Phase 3 | 2021-06-18 |
| Completed | Study in Healthy Adult Subjects to Assess the Effect of Phosphate Binders on the Pharmacokinetics of a Single Healthy Volunteers | Phase 1 | 2020-06-15 |
| Completed | Trial Evaluating the Efficacy and Safety of Oral Vadadustat Once Daily (QD) and Three Times Weekly (TIW) for t Anemia | Phase 3 | 2020-05-27 |
| Completed | Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Vadadustat in Hemodialysis Subjects Wi Anemia Associated With Chronic Kidney Disease | Phase 1 | 2019-05-28 |
| Completed | Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin Alfa Anemia, Dialysis-dependent Chronic Kidney Disease | Phase 2 | 2019-01-31 |
| Completed | Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of Vadadustat Drug Interaction Potentiation, Pharmacokinetics | Phase 1 | 2018-10-03 |
| Completed | A Study in Evaluating Bioequivalence of Test and Reference Vadadustat 450 MG and 150 MG Tablets and to Determi Healthy | Phase 1 | 2018-08-03 |
| Completed | Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide Drug Interaction Potentiation | Phase 1 | 2018-07-20 |
| Completed | Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin Drug Interaction Potentiation | Phase 1 | 2018-07-20 |
| Completed | Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simv Drug Interaction Potentiation | Phase 1 | 2018-06-17 |
| Completed | A Single Dose Study of Oral Vadadustat in Subjects With Normal and Impaired Hepatic Function Hepatic Impairment | Phase 1 | 2018-06-12 |
| Completed | A Study in Evaluating Bioequivalence Between Test and Reference Formulations of Vadadustat Tablets in Healthy Healthy | Phase 1 | 2018-04-12 |
| Completed | A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejecti Heart Failure With Preserved Ejection Fraction | Phase 2 | 2017-11-07 |
| Completed | A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Type 2 Diabetes Mellitus With Diabetic Nephropathy | Phase 2 | 2017-08-01 |
| Withdrawn | Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-De Anemia, Dialysis-Dependent Chronic Kidney Disease | Phase 3 | 2017-08-01 |
| Terminated | Study to Evaluate Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Wh Anemia, Dialysis-Dependent Chronic Kidney Disease | Phase 2 | 2017-05-02 |
| Completed | Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Dialysis-Dependent Chronic Kidn Anemia, Dialysis Dependent Chronic Kidney Disease | Phase 2 | 2016-12-01 |
| Completed | Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Anemia, Non-dialysis Dependent Chronic Kidney Disease | Phase 2 | 2016-10-01 |
| Completed | Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Anemia, Dialysis-Dependent Chronic Kidney Disease | Phase 3 | 2016-08-01 |
| Completed | Efficacy and Safety Study to Evaluate Vadadustat for the Correction or Maintenance Treatment of Anemia in Part Anemia, Dialysis-Dependent Chronic Kidney Disease | Phase 3 | 2016-07-01 |
| Completed | Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Anemia, Non-Dialysis-Dependent Chronic Kidney Disease | Phase 3 | 2016-02-01 |
| Completed | Study to Evaluate Vadadustat for the Correction of Anemia in Participants With Non-dialysis-dependent Chronic Anemia, Non-Dialysis-Dependent Chronic Kidney Disease | Phase 3 | 2015-12-01 |
| Completed | Effect of AKB-6548 on the Pharmacokinetics of Celecoxib Healthy Volunteers | Phase 1 | 2015-07-01 |
| Completed | Relative Bioavailability of Two Formulations of AKB-6548 and the Food Effect of a New Tablet in Healthy Adult Healthy | Phase 1 | 2015-04-01 |
| Completed | Effects of Ferrous Sulfate on the Pharmacokinetics of AKB-6548 Healthy Volunteers | Phase 1 | 2014-12-01 |
| Completed | 16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requ Anemia, End Stage Renal Disease | Phase 2 | 2014-09-10 |
| Completed | Effect of AKB-6548 on Cardiac Repolarization Intervals in Healthy Volunteers Healthy Volunteers | Phase 1 | 2014-01-01 |
| Completed | 20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia Anemia, Chronic Kidney Disease | Phase 2 | 2013-07-23 |
| Completed | 42-Day Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia Anemia, Kidney Disease | Phase 2 | 2011-06-15 |
| Completed | Safety and Efficacy Study for AKB-6548 in Participants With Chronic Kidney Disease and Anemia Anemia, Kidney Disease | Phase 2 | 2010-10-21 |
| Completed | Study to Assess the Safety and Pharmacokinetics of AKB-6548 in Participants With Chronic Kidney Disease (CKD), Chronic Kidney Disease | Phase 2 | 2010-07-08 |