| Not Yet Recruiting | AYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS) NCT07454460 | Milton S. Hershey Medical Center | N/A |
| Recruiting | Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection NCT06803329 | VA Office of Research and Development | N/A |
| Enrolling By Invitation | Optimizing Medical Decisions and Care for Adult Orphans NCT07465770 | Chang Gung University | N/A |
| Recruiting | Sisters of Heart (Hermanas de Corazón): A Community Health Worker Initiative for Improving Heart Health in Mig NCT07111026 | Emory University | N/A |
| Recruiting | Evaluating and Implementing The CONNECT Program - a Group-Based Telehealth Intervention to Reduce Social Isola NCT07107906 | University of Manitoba | N/A |
| Recruiting | CAPABLE Care + Connect NCT07123298 | Johns Hopkins University | N/A |
| Recruiting | Fostering Agricultural Relationships and Meaning - Thriving on Kinship NCT07218965 | Ohio State University | N/A |
| Enrolling By Invitation | Keep Social Study for Young Adults NCT07005817 | University of North Carolina, Chapel Hill | N/A |
| Active Not Recruiting | Health Surveillance at University of Applied Science Hamburg (HAW) NCT07089914 | Jacobs University Bremen gGmbH | — |
| Active Not Recruiting | Social Prescribing and Relationship Cognitive Strategies (SPARCS) NCT06656975 | University of Michigan | N/A |
| Recruiting | Need to be Needed (N2BN) Intervention NCT06510439 | Temple University | N/A |
| Recruiting | Increasing Veterans' Social Engagement and Connectedness NCT06467214 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Adaptation and Implementation of an Intensive Geriatric Service Worker (IGSW) Model of Care for Socially Isola NCT06603610 | Unity Health Toronto | N/A |
| Active Not Recruiting | Effectiveness of a Mobile Application in Improving Employees' Social Well-being. NCT06495801 | University of Eastern Finland | N/A |
| Recruiting | Intervening on Opioid Use and Loneliness NCT06458335 | University of Rochester | N/A |
| Not Yet Recruiting | e-Intervention Enhancing Mental Health in Adolescents NCT06556576 | Fundació Sant Joan de Déu | N/A |
| Not Yet Recruiting | Community Navigators NCT06594029 | Temple University | N/A |
| Enrolling By Invitation | Evaluating Implementation and Impact of the Adapted Choose to Move (CTM) Program NCT06252259 | University of British Columbia | N/A |
| Completed | Auditory-Cognitive Dual-Task Intervention for Older Adults With Hearing Loss NCT06486285 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Walk and Talk: Connecting People With Psoriasis NCT06726213 | Royal Free Hospital NHS Foundation Trust | N/A |
| Not Yet Recruiting | Use of a Social Assistance Robot in a Population of Children Subjected to Prolonged Isolation NCT06405620 | University Hospital, Toulouse | N/A |
| Recruiting | The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function NCT06335836 | The First Affiliated Hospital with Nanjing Medical University | — |
| Completed | Social Functions to Promote Home-based Cognitive Training NCT06175299 | Florida State University | N/A |
| Enrolling By Invitation | Evaluating Implementation and Impact of Provincial Scale-up of the Adapted Choose to Move (CTM) Program NCT06446414 | University of British Columbia | N/A |
| Completed | Digital Gaming Intervention for Older People in Long-term Care NCT06018974 | University of Oulu | N/A |
| Recruiting | LEAPTogether: An Intergenerational Intervention to Address Loneliness and Social Isolation NCT05831475 | Cedars-Sinai Medical Center | N/A |
| Enrolling By Invitation | Provincial Scale-up of Choose to Move (CTM) Phase 4 NCT06434298 | University of British Columbia | N/A |
| Recruiting | Telepsychiatry for Social Isolation in Youths NCT06138301 | Azienda Ospedaliera Universitaria Integrata Verona | N/A |
| Completed | The Impact of Performing Arts on Mental Health, Social Connection, and Creativity in University Students NCT06542003 | National University of Singapore | N/A |
| Completed | The Impact of a Telephone Reminiscence Program NCT05977608 | University of Connecticut | N/A |
| Completed | Study 1: Social Engage Coaching R61 Phase NCT05745493 | University of Rochester | N/A |
| Unknown | Determining How Indoor Lighting Affects the Brain Health of Older Adults NCT05978934 | Well Living Lab, Inc. | N/A |
| Completed | The Feasibility, Acceptability and Preliminary Efficacy of a Group Intervention to Reduce Loneliness NCT05831813 | University of Amsterdam | N/A |
| Completed | A Mixed Methods Randomized Controlled Trial Evaluating the Hans Kai Program NCT03949725 | University of Manitoba | N/A |
| Completed | Empower@Home:Connected - Feasibility and Preliminary Effect Study NCT05732740 | University of Michigan | N/A |
| Unknown | Effectiveness of a Communication Device in Home Care Services in Norway: Does Komp Make Older Adults Feel Happ NCT05919355 | Oslo Metropolitan University | N/A |
| Unknown | Psychosocial Blended Group Intervention RCT NCT05867758 | University of Padova | N/A |
| Completed | The Social Engagement Project: Addressing Isolation with Women Affected by Violence NCT05574192 | University of British Columbia | N/A |
| Completed | Physical Rehabilitation Intervention With Protein Supplementation for People With Problematic Substance Use an NCT05700305 | University of Dublin, Trinity College | — |
| Recruiting | Developing and Assessing an Innovative Exergaming Technology for Older Adults Living in Long-term Care Homes NCT05130203 | University of Toronto | N/A |
| Unknown | Refugee Mental Health and Wellness Pilot Study NCT05031247 | University of California, Los Angeles | N/A |
| Unknown | Telematic Support Group in Patients With Feelings of Loneliness and Social Isolation NCT05520450 | Corporacion Parc Tauli | — |
| Completed | Combatting Social Isolation in Older Adults NCT05426837 | Florida State University | N/A |
| Completed | Reducing Isolation and Feeling of Loneliness During Critical Illness NCT05537311 | Kirby Mayer | N/A |
| Completed | Museum Prescription by a Physician for a Visit to the MBAM NCT05445453 | Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal | N/A |
| Completed | Perception of Appearance and Social Acceptance Between Cleft and Non-Cleft Children in Early Adolescence NCT06539572 | Chang Gung Memorial Hospital | — |
| Completed | Culture and Well-Being for Latinos NCT05244733 | University of Rochester | N/A |
| Active Not Recruiting | Digital Nutrition Intervention for Older Adults NCT05220631 | The University of Texas at San Antonio | N/A |
| Unknown | Evolution and Adaptation to Caregiver of a Socio-geriatric Evaluation NCT05062590 | Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal | N/A |
| Completed | Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study) NCT05319301 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | N/A |
| Withdrawn | The CONNECT Program: Testing a Telephone-Based Mental Health Intervention for Older Adults NCT05120765 | University of Manitoba | N/A |
| Completed | Efficacy of a Brief Online Mindfulness and Self-Compassion Intervention (Mind-OP+) to Increase Connectedness NCT05871554 | University of Regina | N/A |
| Completed | Virtual Guided Tour of the MMFA for Prevention of Social Isolation NCT05046288 | Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal | N/A |
| Unknown | COVID-19 and Social Isolation and Loneliness Trial NCT05228782 | Mount Sinai Hospital, Canada | N/A |
| Unknown | Intergenerational Program for Social Isolation and Loneliness in Older Adults Discharged From the Emergency De NCT05998343 | Mount Sinai Hospital, Canada | N/A |
| Unknown | Virtual Yoga for Social Isolation and Loneliness in Rural Veterans NCT05431166 | Oregon Health and Science University | N/A |
| Completed | Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study) NCT04897802 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Unknown | Acceptability/Feasibility of COVID-19 Intervention NCT05019053 | Ohio University | N/A |
| Completed | Discrimination and the Brain-Gut-Microbiome (BGM) Axis NCT05120908 | University of California, Los Angeles | — |
| Completed | Evaluation of the Wits Workout Wellness Program for Older Adults NCT04928885 | University of Illinois at Chicago | N/A |
| Completed | Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study) NCT04902235 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Completed | COVID-19 Versus Neurological Impairment, Physical Activity, Social Contacts and Education NCT04934085 | University of Rzeszow | — |
| Completed | Evaluating Quebec's Red-Cross Intervention NCT05099042 | Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal | N/A |
| Completed | Connect for Caregivers NCT04919070 | University of Rochester | N/A |
| Completed | The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors NCT04913363 | University of Virginia | N/A |
| Completed | The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT) NCT07204444 | University of Florida | N/A |
| Unknown | An Effectiveness-implementation Hybrid Study of Social Prescribing in a Singapore Community Hospital Setting NCT04840420 | Bright Vision Hospital | N/A |
| Completed | A 3-month Cycle of Virtual Guided Tours to Promote Health in Older Community Members in a Context of COVID-19 NCT04593433 | Jewish General Hospital | N/A |
| Completed | Engage Coaching for Latinos NCT04875065 | University of Rochester | N/A |
| Withdrawn | Connection for Latinos Caring for a Loved One With Dementia NCT04593628 | University of Rochester | N/A |
| Completed | International Students Intervention NCT04945902 | Purdue University | N/A |
| Completed | Mindfulness to Reduce Loneliness in Older Caregivers NCT04560088 | University of Rochester | N/A |
| Completed | Online Singing Interventions for Postnatal Depression in Times of Social Isolation: a Single Arm Study NCT04857593 | King's College London | N/A |
| Completed | The Effects of Telerehabilitation on Muscle Function, Physical Activity and Sleep in Cystic Fibrosis During Pa NCT04742049 | Hacettepe University | N/A |
| Recruiting | The VESPA Pilot Study NCT04756245 | Wake Forest University | N/A |
| Completed | Utilizing Novel Information Technology to Promote Exercise and Well-Being in Adolescents and Young Adults With NCT03778658 | Milton S. Hershey Medical Center | N/A |
| Completed | Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients NCT04604158 | Gillian Gresham | N/A |
| Completed | the Role of Technology in Elderly Patients NCT05000099 | Centre Hospitalier Universitaire Vaudois | — |
| Completed | Using Social Connectedness to Increase Physical Activity NCT04573972 | Carnegie Mellon University | N/A |
| Completed | Evaluating Impact and Implementation of Choose to Move (Phase 4) NCT05678985 | University of British Columbia | N/A |
| Completed | The Effectiveness of Video-Based Exercises in Young Adults NCT04346966 | Istinye University | N/A |
| Unknown | The Effectiveness of Telerehabilitation-Based Exercises in Elderly People NCT04346940 | Istinye University | N/A |
| Completed | Engage Psychotherapy to Promote Connectedness in Caregivers NCT04176601 | University of Rochester | N/A |
| Completed | Evaluation of the Nextdoor KIND Challenge NCT04398472 | Swinburne University of Technology | N/A |
| Completed | Telephone Calls for Health for Homebound Older Adults NCT04595708 | University of Texas at Austin | N/A |
| Completed | Mental Health Impact of the COVID-19 Pandemic Among Migrants in Chile NCT04497636 | Pontificia Universidad Catolica de Chile | — |
| Completed | Tertulias Social Isolation Women's Groups Study NCT04254198 | University of New Mexico | N/A |
| Completed | Effect of Social Isolation on Physical Activity Level, and Kinesophobia in Heart Rhythm Disorders During Pande NCT04818697 | Hacettepe University | — |
| Unknown | The PREPARE for COVID Trial NCT04392115 | Ottawa Hospital Research Institute | N/A |
| Completed | Rural Dementia Caregiver Project NCT04428112 | University of California, San Francisco | N/A |
| Completed | Physical Activity Levels of Hypertensive and Healthy Individuals Under Social Isolation During the COVID-19 Pa NCT04583345 | Ebru Calik Kutukcu | — |
| Completed | Does Quality of Life Decline During the COVID-19 Pandemic and Can we Change Behaviour to Improve Poor Quality NCT04522128 | University of Manchester | N/A |
| Completed | Community Health Workers Against COVID19 NCT04426305 | University Ghent | N/A |
| Completed | Impact of COVID-19 Pandemic on Depression and Quality of Life NCT04394078 | Okan University | — |
| Completed | Positive Affect Regulation sKills at Northwestern University NCT04367922 | Northwestern University | N/A |
| Active Not Recruiting | First Level Socio-geriatric Evaluation: ESOGER Databank NCT04393649 | Jewish General Hospital | — |
| Completed | Video-Based Exercises and Well-Being During Social Isolation NCT04335851 | Biruni University | N/A |
| Completed | COVID Feel Good-An Easy Self-Help Virtual Reality Protocol to Overcome the Psychological Burden of Coronavirus NCT06850376 | Istituto Auxologico Italiano | N/A |
| Completed | Physical Activity During Social Isolation NCT04339491 | Istanbul University - Cerrahpasa | — |
| Completed | Studying the Association Between Folic Acid Deficiency and Social Isolation for Elderly Patients NCT04180800 | University Hospital, Strasbourg, France | — |
| Completed | Choose to Move - Next Steps: Can 'Booster Sessions' Sustain Health Benefits of an Effective, Scaled-up, Health NCT04592614 | University of British Columbia | N/A |
| Completed | Depression, Anxiety and Social Relationships as Risk Factors for Dementia NCT04786561 | Norwegian Centre for Ageing and Health | — |
| Completed | ENRED@TE. Social Support in Southern Spain. Interventional Study NCT04567940 | Maimónides Biomedical Research Institute of Córdoba | N/A |
| Completed | Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older NCT04281654 | George Mason University | N/A |
| Completed | Effects of Montreal Museum of Fine Arts Visits and Older Community Dwellers With a Precarious State NCT03962985 | Jewish General Hospital | N/A |
| Completed | 2nd AC+: New Village Model NCT04323176 | University of California, San Diego | N/A |
| Completed | Medico-social Mediation on the Prevention of the Return to Emergencies Among People in a Precarious Social Sit NCT03660215 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | The Ageing in a Networked Society -Social Experiment Study NCT04242628 | University of Milano Bicocca | N/A |
| Terminated | Evaluating a Primary-Care Group-based Mindfulness Program NCT03662581 | McMaster University | N/A |
| Completed | A Personalized Health Behavior System NCT03538158 | Weill Medical College of Cornell University | N/A |
| Completed | Community Paramedicine at Home NCT02835989 | McMaster University | N/A |
| Completed | Peer Support Intervention to Mitigate Social Isolation and Stigma of Adolescent Motherhood in Zimbabwe NCT05213182 | West Chester University of Pennsylvania | Phase 2 |
| Unknown | PHYSICAL ACTIVITY AS A MEASURE OF IMPROVING THE EMOTIONAL STATE AND SOCIALIZATION IN THE ELDERLY NCT04072185 | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | N/A |
| Completed | AGE-ON 2.0: Expanding and Evaluating a Tablet Training Program for Older Adults NCT03472729 | McMaster University | N/A |
| Completed | The Impact of Community Exercise on Social Connectedness and Falls in Older Adults: Leveraging Exercise to Age NCT03624049 | Cedars-Sinai Medical Center | N/A |
| Completed | Connecting People Implementation Study NCT03945994 | University of York | N/A |
| Completed | Evaluating Impact and Implementation of Choose to Move (Phase 3) NCT05497648 | University of British Columbia | N/A |
| Unknown | Community-based Pro-Active Monitoring Program (CAMP) and Older Adults NCT04785664 | University of Rome Tor Vergata | N/A |
| Completed | HARP-Project 1 Cognitive Training NCT03293823 | University of Rochester | N/A |
| Completed | Bridging Community Gaps Photovoice NCT03291717 | Boston University Charles River Campus | N/A |
| Completed | Blue Star Cares: Innovative Approaches to Helping Military-Connected Caregivers NCT03336190 | University of Southern California | N/A |
| Completed | Tele-BA for Home-Delivered Meals Clients NCT04131790 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | "Recovery 4 US" - A Photovoice-based Social Media Program NCT03266614 | Boston University Charles River Campus | N/A |
| Completed | KOSO (Keep On Stepping On)/ Stepping Online NCT02774889 | University of Wisconsin, Madison | N/A |
| Completed | Implementation and Impact of an Online Tool Used in Primary Care to Improve Income Security NCT02959866 | Unity Health Toronto | N/A |
| Completed | Promoting Walking in Older Adults Living in Independent Living Communities in Northern Ireland: A Feasibility NCT02596672 | Queen's University, Belfast | N/A |
| Completed | Mobilizing Community Networks to Optimize Child Well-being NCT02622399 | Boston Medical Center | N/A |
| Completed | Stay Healthy In Nature Everyday: Family Nature Outings in a Low Income Population NCT02623855 | UCSF Benioff Children's Hospital Oakland | N/A |
| Completed | Community Intervention to Reduce Social Isolation in Elderly People: a Mixed Methods Multi-approach Evaluation NCT03142048 | Public Health Agency of Barcelona | N/A |
| Completed | Building Wealth and Health Network: A Microfinance/TANF Demonstration Project NCT02577705 | Center for Hunger-Free Communities | N/A |
| Unknown | Integrating Lonely Elderly Patients in Workshops in a Cartoon Museum: An Efficacy Study NCT02047435 | Research Unit Of General Practice, Copenhagen | N/A |
| Completed | Evaluating the RelAte Mealtime Program as an Intervention to Treat Social Isolation and Improve Cooking Behavi NCT02007551 | University of Dublin, Trinity College | N/A |
| Completed | Decreasing Loneliness in Older Adults NCT01842984 | Tel Aviv University | N/A |
| Completed | Discharge Functional Status and Rehospitalization in the Elderly NCT02041585 | Northwestern University | — |
| Completed | A Personalized Reminder Information and Social Management System NCT01497613 | University of Miami | N/A |