Trials / Conditions / Smith-Lemli-Opitz Syndrome

Smith-Lemli-Opitz Syndrome

16 registered clinical trials studyying Smith-Lemli-Opitz Syndrome — 3 currently recruiting.

Status	Trial	Sponsor	Phase
Completed	Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocog NCT05642221	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	—
Completed	Baby Detect : Genomic Newborn Screening NCT05687474	Centre Hospitalier Universitaire de Liege	—
Recruiting	Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol Metabo NCT05047354	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	—
Completed	Smith-Lemli-Opitz Syndrome and Cholic Acid NCT03720990	University of Nebraska	Phase 1 / Phase 2
Enrolling By Invitation	Early Check: Expanded Screening in Newborns NCT03655223	RTI International	—
Terminated	SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol Supplementation NCT01434745	Oregon Health and Science University	N/A
Withdrawn	Novel Treatment for Syndromic Ichthyoses NCT01110642	Northwestern University	Phase 2
Terminated	Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz Syndrome NCT01356420	Oregon Health and Science University	N/A
Recruiting	Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS) NCT01773278	University of Colorado, Denver	Phase 2
Completed	Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome NCT00114634	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Phase 2
Completed	Simvastatin Therapy in Smith-Lemli-Opitz Syndrome NCT00064792	Forbes Porter, M.D.	Phase 2
Completed	Estimation of the Carrier Frequency and Incidence of Smith-Lemli-Opitz Syndrome in African Americans NCT00017732	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	—
Completed	Prenatal Screening For Smith-Lemli-Opitz Syndrome NCT00070850	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	—
Completed	Study of Smith-Lemli-Opitz Syndrome NCT00001721	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	—
Completed	Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome NCT00272844	Boston Children's Hospital	Phase 1 / Phase 2
Unknown	Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz Syndrome NCT00004347	National Center for Research Resources (NCRR)	Phase 2