| Not Yet Recruiting | Optimising Breathing Support at Extubation in Very Preterm Infants: A Clinical Study NCT07251790 | Murdoch Childrens Research Institute | N/A |
| Recruiting | Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting NCT07344714 | Mayo Clinic | — |
| Not Yet Recruiting | Utilization of Lung Ultrasound Score in Decision for Minimally Invasive Surfactant Administration NCT07442669 | Hackensack Meridian Health | N/A |
| Not Yet Recruiting | Speed of Lung Inflation During Ventilation of Extremely Preterm Infants NCT07101419 | Murdoch Childrens Research Institute | N/A |
| Recruiting | Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam NCT07098910 | Karolinska Institutet | N/A |
| Recruiting | Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa NCT06554522 | Indiana University | Phase 4 |
| Recruiting | Prophylactic Surfactant by Thin Endotracheal Catheter for Preterm Infants At Birth: the ProTeCt Trial NCT06557551 | University College Dublin | N/A |
| Recruiting | Effect of Implementing Evidence Based Practices on Prevention of Associated Nasal Pressure Injuries Among Pret NCT06642285 | Kafrelsheikh University | N/A |
| Recruiting | The NONA-LISA Trial NCT05609877 | Rigshospitalet, Denmark | N/A |
| Completed | Recombinant Surfactant Protein D (rfhSP-D) to Prevent Neonatal Chronic Lung Disease NCT05898633 | University College, London | Phase 1 |
| Unknown | Safety and Efficacy of Intrapulmonary Percussive Ventilation in Preterm Infants NCT06229821 | Augusta University | N/A |
| Recruiting | Physiologically Based Cord Clamping To Improve Neonatal Outcomes In Moderate And Late Preterm Newborns NCT06280872 | Queen Fabiola Children's University Hospital | N/A |
| Unknown | REspiratory MEchanics for Delivering Individualised Exogenous Surfactant NCT05791331 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Completed | Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment - Validation Study NCT05615428 | Rigshospitalet, Denmark | — |
| Recruiting | 30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants NCT03825835 | University of Alberta | N/A |
| Terminated | PAL to Improve Oral Feeding for Infants With Chronic Lung Disease NCT05446389 | University of Missouri-Columbia | N/A |
| Completed | Novel Low Cost Bubble CPAP as an Alternative Respiratory Support in Low Resource Setting NCT06082674 | Ilocos Training and Regional Medical Center | Phase 2 |
| Unknown | Intratracheal Budesonide With Surfactant to Prevent Bronchopulmmonary Dysplasia. NCT04862377 | Hospital Clinic of Barcelona | Phase 3 |
| Recruiting | Effect of Nasal CPAP Versus NIPPV On Diaphragm Electrical Activity (Edi) In VLBW Preterm Infants NCT06295484 | Sunnybrook Health Sciences Centre | N/A |
| Withdrawn | nHFOV Versus Invasive Conventional Ventilation for Preterm Neonates With Respiratory Distress Syndrome NCT04914715 | Indus Hospital and Health Network | N/A |
| Completed | Effect of Chest Physiotherapy on the Development of Preterm Infants. NCT04689386 | Universidad de Murcia | N/A |
| Completed | Neonatal Cardio-Pulmonary Outcome Measure NCT04324957 | Asir John Samuel | — |
| Unknown | Combined Lung Ultrasounds and Transthoracic Electrical Bioimpedance in Preterm Infants With Respiratory Distre NCT04359134 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact NCT03969992 | Aerogen Pharma Limited | Phase 2 |
| Unknown | Ventilator Weaning Outcome Between NIV-NAVA and Nasal CPAP (or IMV ) Modes in Premature Neonates NCT04118400 | Taipei Medical University Hospital | — |
| Unknown | Budesonide With Intratracheal Surfactants in Extremely Preterm Infants NCT04019106 | University of Manitoba | Phase 1 / Phase 2 |
| Active Not Recruiting | Respiratory Effect of the LISA Method with Sedation by Propofol Versus Absence of Sedation. NCT04016246 | University Hospital, Grenoble | Phase 3 |
| Completed | Open Lung Strategy During Non-Invasive Respiratory Support of Very Preterm Infants in the Delivery Room NCT05031650 | Dokuz Eylul University | N/A |
| Completed | Feasibility Study - Neofact NCT04086095 | University Hospital Tuebingen | N/A |
| Unknown | Pressure HIgh or LOw DElivered to Preterm Newborns in the Delivery ROOM NCT06123845 | ASST Fatebenefratelli Sacco | N/A |
| Terminated | Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants NCT03558737 | University of Utah | N/A |
| Completed | Physiological Changes With High-Flow Nasal Cannula NCT03700606 | Sharp HealthCare | N/A |
| Unknown | Crossover Comparison of Tidal Volume Delivery During Nasal Intermittent Positive Pressure Ventilation in Prete NCT04326270 | Arkansas Children's Hospital Research Institute | N/A |
| Completed | Enteral Nutrition Tolerance And REspiratory Support (ENTARES) NCT03548324 | University of Turin, Italy | N/A |
| Unknown | Effect of Steroid Administration on Maternal Blood Levels of hLPCAT1 mRNA NCT03562182 | Wayne State University | — |
| Completed | Risk Factors of Meconium Obstruction and Respiratory Distress Syndrome in Preterm Infants NCT03513640 | Seoul National University Hospital | — |
| Completed | The Role of Circuit Flow During Mechanical Ventilation of Neonates NCT03306524 | Cambridge University Hospitals NHS Foundation Trust | N/A |
| Completed | Immediate Treatment Outcomes of b-CPAP vs Oxygen Therapy in Preterm Babies Presenting With RDS at KCMC NCT03620448 | Kilimanjaro Christian Medical Centre, Tanzania | N/A |
| Completed | Comparison of Two Nasal Interface for CPAP in Preterm NCT03212508 | Dartmouth-Hitchcock Medical Center | — |
| Completed | Clinical RD (Respiratory Distress) Score for Objective Decision Making for Surfactant Therapy NCT03273764 | Lady Hardinge Medical College | — |
| Completed | Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respirato NCT01941745 | Tufts Medical Center | Phase 2 |
| Completed | Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndro NCT01473264 | Clarassance, Inc. | Phase 1 / Phase 2 |