Clinical Trials Directory

Trials / Conditions / Refractory Plasma Cell Myeloma

Refractory Plasma Cell Myeloma

80 registered clinical trials studyying Refractory Plasma Cell Myeloma5 currently recruiting.

StatusTrialSponsorPhase
Active Not RecruitingSelinexor, Daratumumab, Carfilzomib and Dexamethasone for the Treatment of High-Risk, Recurrent or Refractory
NCT04756401
Academic and Community Cancer Research UnitedPhase 2
RecruitingRadioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple
NCT05363111
City of Hope Medical CenterPhase 1
Active Not RecruitingVenetoclax and Tocilizumab for the Treatment of Patients With Relapsed or Refractory t(11;14) Multiple Myeloma
NCT05391750
Emory UniversityPhase 1
Active Not RecruitingBortezomib and Pembrolizumab With or Without Pelareorep for the Treatment of Relapsed or Refractory Multiple M
NCT05514990
University of Southern CaliforniaPhase 1 / Phase 2
RecruitingNon-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With
NCT05312255
Roswell Park Cancer InstituteN/A
Active Not RecruitingGenetically Engineered Cells (MUC1-Activated T-Cells) for the Treatment of MUC1 Positive Recurrent or Refracto
NCT05411497
Mayo ClinicPhase 1
TerminatedImmunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (
NCT05288062
Mayo ClinicPhase 2
Active Not RecruitingIsatuximab, Carfilzomib, and Pomalidomide for the Treatment of Relapsed or Refractory Multiple Myeloma
NCT04850599
OHSU Knight Cancer InstitutePhase 2
TerminatedPembrolizumab for the Treatment of Relapsed or Refractory Multiple Myeloma After Anti-BCMA CAR-T Therapies
NCT05191472
Alfred Chung, MDPhase 2
TerminatedPanobinostat in Combination With Daratumumab, Bortezomib and Dexamethasone for the Treatment of Relapsed/Refra
NCT04956302
Abdullah KhanPhase 1
TerminatedBelantamab Mafodotin, Lenalidomide, and Daratumumab for the Treatment of Relapsed, Refractory, or Previously U
NCT04892264
Mayo ClinicPhase 1
Active Not RecruitingLow-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neop
NCT04640779
Mayo ClinicPhase 1
TerminatedDaratumumab, Azacitidine, and Dexamethasone for Treatment of Patients With Recurrent or Refractory Multiple My
NCT04407442
University of California, San FranciscoPhase 2
RecruitingLeflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma
NCT04508790
City of Hope Medical CenterPhase 2
Active Not RecruitingNivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in P
NCT04205409
University of WashingtonPhase 2
CompletedHypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-cell Therapy
NCT04409314
University of California, San Francisco
TerminatedSerial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
NCT03878524
OHSU Knight Cancer InstitutePhase 1
WithdrawnIxazomib and Dexamethasone With or Without Venetoclax in Treating Patients With Non-t(11;14) Relapsed or Refra
NCT03856112
National Cancer Institute (NCI)Phase 1 / Phase 2
RecruitingCS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multipl
NCT03710421
City of Hope Medical CenterPhase 1
CompletedMetformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma
NCT03829020
Mayo ClinicPhase 1
WithdrawnDaratumumab, Bortezomib, and Dexamethasone With or Without Venetoclax in Treating Patients With Relapsed or Re
NCT03701321
National Cancer Institute (NCI)Phase 1 / Phase 2
Active Not RecruitingDaratumumab, Bortezomib, and Dexamethasone Followed by Daratumumab, Ixazomib, and Dexamethasone in Treating Pa
NCT03763162
M.D. Anderson Cancer CenterPhase 2
CompletedDexamethasone, Elotuzumab, and Pomalidomide in Treating Patients With Refractory Multiple Myeloma
NCT03713294
Mayo ClinicPhase 2
TerminatedAbatacept, Ixazomib Citrate, and Dexamethasone in Treating Patients With Multiple Myeloma Resistant to Chemoth
NCT03457142
Roswell Park Cancer InstitutePhase 2
WithdrawnStudy of Personalized Melphalan Dosing in the Setting of Autologous Transplant
NCT03328936
Ohio State University Comprehensive Cancer CenterPhase 2
WithdrawnTCR Genetically Engineered PBMC and PBSC After Melphalan Conditioning Regimen in Treating Participants With Re
NCT03506802
Jonsson Comprehensive Cancer CenterPhase 1
CompletedPembrolizumab and Radiation Therapy in Patients With Relapsed or Refractory Multiple Myeloma
NCT03267888
Emory UniversityPhase 1 / Phase 2
TerminatedBCMA-Specific CAR T-Cells Combined With a Gamma Secretase Inhibitor (JSMD194) to Treat Relapsed or Persistent
NCT03502577
Fred Hutchinson Cancer CenterPhase 1
TerminatedLenalidomide and Nivolumab in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT03333746
Yvonne EfeberaPhase 2
TerminatedPanobinostat, Carfilzomib, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
NCT03256045
University of WashingtonPhase 2
CompletedImmunotherapy With BCMA CAR-T Cells in Treating Patients With BCMA Positive Relapsed or Refractory Multiple My
NCT03338972
Fred Hutchinson Cancer CenterPhase 1
CompletedMetformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chr
NCT02948283
City of Hope Medical CenterPhase 1
CompletedIxazomib Citrate, Pomalidomide, Dexamethasone, Stem Cell Transplant in Treating Relapsed or Refractory Multipl
NCT03202628
Mayo ClinicPhase 2
CompletedHigh Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in P
NCT03128359
City of Hope Medical CenterPhase 2
RecruitingA Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemi
NCT03017820
Mayo ClinicPhase 1
WithdrawnSimvastatin in Overcoming Chemotherapy Resistance in Patients With Relapsed or Refractory Multiple Myeloma
NCT02971410
Wake Forest University Health SciencesEARLY_Phase 1
TerminatedIbrutinib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Ineligible for Transplan
NCT03015792
Mayo ClinicPhase 1
CompletedIxazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized With NFKB2 Rearrangemen
NCT02765854
Emory UniversityPhase 2
CompletedTesting Nivolumab as a Potential Targeted Treatment in Cancers With Mismatch Repair Deficiency (MATCH-Subproto
NCT04439214
National Cancer Institute (NCI)Phase 2
CompletedTesting AZD4547 as a Potential Targeted Treatment in Cancers With FGFR Genetic Changes (MATCH-Subprotocol W)
NCT04439240
National Cancer Institute (NCI)Phase 2
WithdrawnTesting Dasatinib as a Potential Targeted Treatment in Cancers With DDR2 Genetic Changes (MATCH-Subprotocol X)
NCT04439305
National Cancer Institute (NCI)Phase 2
CompletedLeflunomide in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT02509052
City of Hope Medical CenterPhase 1 / Phase 2
CompletedPanobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patie
NCT02506959
M.D. Anderson Cancer CenterPhase 2
CompletedWild-Type Reovirus, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple My
NCT02514382
University of Southern CaliforniaPhase 1
TerminatedIbrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection
NCT02109224
National Cancer Institute (NCI)Phase 1
CompletedIxazomib Plus Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Relapsed/Refractory Multipl
NCT02119468
City of Hope Medical CenterPhase 1 / Phase 2
CompletedCarfilzomib, Bendamustine Hydrochloride, and Dexamethasone in Treating Patients With Relapsed or Refractory Mu
NCT02095834
M.D. Anderson Cancer CenterPhase 1
TerminatedPomalidomide, Dexamethasone, and Filgrastim-sndz in Treating Patients With Relapsed or Refractory Multiple Mye
NCT01946152
M.D. Anderson Cancer CenterPhase 1 / Phase 2
CompletedPomalidomide or Lenalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myelo
NCT01794039
Mayo ClinicPhase 2
CompletedSonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma
NCT02086552
Mayo ClinicPhase 2
CompletedSMAC Mimetic LCL161 Alone or With Cyclophosphamide in Treating Patients With Relapsed or Refractory Multiple M
NCT01955434
Mayo ClinicPhase 2
CompletedTrametinib and Akt Inhibitor GSK2141795 in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT01989598
National Cancer Institute (NCI)Phase 2
CompletedS1304, Carfilzomib and Dexamethasone for Treating Patients With Relapsed or Refractory Myeloma
NCT01903811
SWOG Cancer Research NetworkPhase 2
TerminatedDesipramine Hydrochloride and Filgrastim For Stem Cell Mobilization in Patients With Multiple Myeloma Undergoi
NCT01899326
Albert Einstein College of MedicineN/A
CompletedBortezomib, Melphalan, and Total-Body Irradiation Before Stem Cell Transplant in Treating Patients With Multip
NCT01936090
Mayo ClinicPhase 1
CompletedCarfilzomib and Melphalan Before Stem Cell Transplant in Treating Patients With Multiple Myeloma
NCT01842308
Mayo ClinicPhase 1 / Phase 2
TerminatedPaclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Relapsed or Refractory Multip
NCT01646762
Mayo ClinicPhase 2
CompletedHydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refra
NCT01689987
OHSU Knight Cancer InstitutePhase 1
CompletedViral Therapy in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT01533194
National Cancer Institute (NCI)Phase 1
CompletedFilanesib and Carfilzomib in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leu
NCT01372540
M.D. Anderson Cancer CenterPhase 1
CompletedBusulfan, Melphalan, and Bortezomib Before First-Line Stem Cell Transplant in Treating Patients With Multiple
NCT01605032
Albert Einstein College of MedicinePhase 2
CompletedIxazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib
NCT01415882
Mayo ClinicPhase 2
Completed90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Periphe
NCT01503242
Fred Hutchinson Cancer CenterPhase 1
CompletedPanobinostat and Carfilzomib in Treating Participants With Relapsed or Refractory Multiple Myeloma
NCT01301807
M.D. Anderson Cancer CenterPhase 1
CompletedVeliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma
NCT01326702
National Cancer Institute (NCI)Phase 1 / Phase 2
CompletedBortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Don
NCT01163357
City of Hope Medical CenterPhase 1
CompletedVismodegib After Stem Cell Transplant in Treating Patients With High-Risk First Remission or Relapsed Multiple
NCT01330173
National Cancer Institute (NCI)Phase 1
WithdrawnRO4929097 After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma
NCT01251172
National Cancer Institute (NCI)Phase 2
TerminatedDonor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
NCT01028716
Fred Hutchinson Cancer CenterPhase 2
CompletedAutologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients
NCT01008462
Fred Hutchinson Cancer CenterPhase 2
CompletedAZD6244 (Selumetinib) in Treating Patients With Multiple Myeloma
NCT01085214
National Cancer Institute (NCI)Phase 2
TerminatedBortezomib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Undergoing Stem Cell Tr
NCT02353468
University of Colorado, DenverPhase 2
CompletedLenalidomide, Thalidomide and Dexamethasone in Treating Participants With Relapsed or Refractory Multiple Myel
NCT00966693
M.D. Anderson Cancer CenterPhase 1 / Phase 2
CompletedFludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by
NCT00789776
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedAutologous or Syngeneic Stem Cell Transplant Followed by Donor Stem Cell Transplant and Bortezomib in Treating
NCT00793572
Fred Hutchinson Cancer CenterPhase 2
CompletedLenalidomide, Dexamethasone, and Clarithromycin in Treating Patients Who Have Undergone Stem Cell Transplant f
NCT00445692
Fred Hutchinson Cancer CenterPhase 2
CompletedVaccine Therapy With or Without Cyclophosphamide in Treating Patients With Recurrent or Refractory Multiple My
NCT00450814
Mayo ClinicPhase 1 / Phase 2
CompletedTacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease i
NCT00105001
Fred Hutchinson Cancer CenterPhase 2
CompletedBortezomib and Flavopiridol in Treating Patients With Recurrent or Refractory Indolent B-Cell Neoplasms
NCT00082784
National Cancer Institute (NCI)Phase 1
CompletedFR901228 in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT00066638
National Cancer Institute (NCI)Phase 2