| Not Yet Recruiting | Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer NCT06751394 | Sixth Affiliated Hospital, Sun Yat-sen University | Phase 2 |
| Recruiting | The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer NCT05628038 | Fudan University | Phase 2 |
| Unknown | PelvEx 4: Advanced Pelvic Malignancy and the Role of the Multi-disciplinary Team Meeting NCT05076305 | St Vincent's University Hospital, Ireland | — |
| Terminated | Hypofractionated Pencil-Beam Scanning Intensity-modulated Proton Therapy (IMPT) in Recurrent Rectal Cancer NCT04827732 | Washington University School of Medicine | N/A |
| Recruiting | Induction Chemotherapy for Locally Recurrent Rectal Cancer NCT04389086 | Catharina Ziekenhuis Eindhoven | Phase 3 |
| Unknown | CTV Exploration of 3D-PT Assisted CT-guided I-125 Seeds Implantation for Recurrent Rectal Cancer NCT04710589 | Peking University Third Hospital | — |
| Unknown | SGM-101 in Locally Advanced and Recurrent Rectal Cancer NCT04642924 | Leiden University Medical Center | Phase 2 / Phase 3 |
| Unknown | Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES) NCT04065984 | London North West Healthcare NHS Trust | N/A |
| Terminated | Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Sprea NCT02110953 | Fox Chase Cancer Center | Phase 1 |
| Completed | Magnetic Resonance-Guided High Intensity Focused Ultrasound for Recurrent Rectal Cancer NCT02528175 | William Chu, MD, MSc, FRCPC | N/A |
| Withdrawn | Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With St NCT02235324 | University of Southern California | Phase 2 |
| Completed | CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surg NCT02232152 | Wake Forest University Health Sciences | Phase 1 |
| Completed | Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer NCT02270606 | Virginia Commonwealth University | Phase 1 |
| Completed | Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Adv NCT02132858 | Fox Chase Cancer Center | — |
| Completed | MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patient NCT02041481 | City of Hope Medical Center | Phase 1 |
| Withdrawn | Short-Infusion Ziv-aflibercept in Treating Patients With Metastatic Colorectal Cancer Receiving Combination Ch NCT01941173 | City of Hope Medical Center | N/A |
| Completed | Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointe NCT01846520 | City of Hope Medical Center | N/A |
| Completed | Comprehensive Gene Sequencing in Guiding Treatment Recommendations Patients With Metastatic or Recurrent Solid NCT01987726 | Ohio State University Comprehensive Cancer Center | — |
| Completed | Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer NCT01923337 | University of California, Davis | Phase 1 |
| Completed | PET-MRI in Diagnosing Patients With Colon or Rectal Cancer NCT01807117 | Case Comprehensive Cancer Center | N/A |
| Completed | 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis NCT01806675 | Sanjiv Sam Gambhir | Phase 1 / Phase 2 |
| Completed | Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab NCT01814501 | John Hays | Phase 2 |
| Terminated | Ipilimumab and Local Radiation for Selected Solid Tumors NCT01769222 | Stanford University | Phase 1 |
| Completed | Phase I/II Trial Evaluating Carbon Ion Radiotherapy for the Treatment of Recurrent Rectal Cancer NCT01528683 | University Hospital Heidelberg | N/A |
| Completed | Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal C NCT01740648 | Ohio State University Comprehensive Cancer Center | Phase 1 |
| Completed | Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors NCT01217450 | National Cancer Institute (NCI) | Phase 1 |
| Withdrawn | Laparoscopic Surgery or Robotic-Assisted Laparoscopic Surgery in Treating Patients With Rectal Cancer That Can NCT01196000 | City of Hope Medical Center | N/A |
| Completed | Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancer NCT01191684 | City of Hope Medical Center | Phase 1 |
| Terminated | Linifanib in Treating Patients With Advanced, Refractory Colorectal Cancer NCT01365910 | Vanderbilt-Ingram Cancer Center | Phase 2 |
| Completed | Supportive Intervention Programs Study NCT01590147 | Wake Forest University | N/A |
| Completed | Radiolabeled Monoclonal Antibody Therapy, Combination Chemotherapy, and Bevacizumab in Treating Patients With NCT01205022 | City of Hope Medical Center | Phase 1 |
| Terminated | Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treati NCT01320683 | City of Hope Medical Center | Phase 2 |
| Completed | Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer NCT01294826 | Swedish Medical Center | Phase 1 |
| Withdrawn | Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colore NCT01270438 | National Cancer Institute (NCI) | Phase 2 |
| Terminated | Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors NCT01233505 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal NCT01285102 | Fox Chase Cancer Center | Phase 1 |
| Terminated | Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Can NCT01238965 | University of Southern California | Phase 1 |
| Completed | RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors NCT01158274 | National Cancer Institute (NCI) | Phase 1 |
| Completed | RO4929097 in Treating Patients With Metastatic Colorectal Cancer NCT01116687 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Azacitidine and Entinostat in Treating Patients With Metastatic Colorectal Cancer NCT01105377 | National Cancer Institute (NCI) | Phase 2 |
| Terminated | Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by Surg NCT00835679 | National Cancer Institute (NCI) | EARLY_Phase 1 |
| Completed | Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer NCT01037790 | Abramson Cancer Center at Penn Medicine | Phase 2 |
| Completed | Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer NCT00826540 | Alliance for Clinical Trials in Oncology | Phase 2 |
| Completed | Vorinostat, Fluorouracil, and Leucovorin Calcium in Treating Patients With Metastatic Colorectal Cancer That H NCT00942266 | Roswell Park Cancer Institute | Phase 2 |
| Completed | Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or Adenoma NCT00754494 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorecta NCT00551421 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Dasatinib in Treating Patients With Previously Treated Metastatic Colorectal Cancer NCT00504153 | National Cancer Institute (NCI) | Phase 2 |
| Terminated | Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer Th NCT00499369 | National Cancer Institute (NCI) | Phase 3 |
| Completed | Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Nec NCT00397384 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer NCT00397878 | National Cancer Institute (NCI) | Phase 2 |
| Completed | VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer NCT00407654 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressi NCT00138177 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Sorafenib, Cetuximab, and Irinotecan in Treating Patients With Advanced or Metastatic Colorectal Cancer NCT00134069 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Ther NCT00645710 | City of Hope Medical Center | Phase 1 / Phase 2 |
| Completed | SB-715992 in Treating Patients With Advanced or Metastatic Colorectal Cancer NCT00103311 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidne NCT00101348 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Phase II Trial of FOLFOX6, Bevacizumab and Cetuximab in Patients With Colorectal Cancer NCT00100841 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatme NCT00091182 | National Cancer Institute (NCI) | Phase 2 |
| Terminated | Vaccine Therapy and Sargramostim With or Without Docetaxel in Treating Patients With Metastatic Lung Cancer or NCT00088933 | National Cancer Institute (NCI) | Phase 1 |
| Completed | GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Ca NCT00084643 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer NCT00087191 | National Cancer Institute (NCI) | N/A |
| Terminated | Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent NCT00070122 | National Cancer Institute (NCI) | Phase 3 |
| Completed | 2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer NCT01821105 | Ohio State University Comprehensive Cancer Center | Phase 2 |
| Completed | Bevacizumab and Cetuximab With or Without Irinotecan in Treating Patients With Irinotecan-Refractory Metastati NCT00077298 | National Cancer Institute (NCI) | Phase 2 |
| Terminated | Neoadjuvant and Adjuvant Capecitabine and Oxaliplatin in Treating Patients With Resectable Liver Metastases Se NCT00070265 | National Cancer Institute (NCI) | Phase 2 |
| Completed | A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, an NCT00060411 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer NCT00052585 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Imatinib Mesylate in Treating Patients With Stage IV Colorectal Cancer NCT00041340 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Live NCT00026234 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer NCT00032110 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction NCT00030498 | National Cancer Institute (NCI) | Phase 1 |
| Completed | 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid NCT00031681 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer NCT00028496 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Recurrent or Persistent Metastatic Colorect NCT00023933 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With NCT00025337 | National Cancer Institute (NCI) | Phase 3 |
| Completed | SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer NCT00005818 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer NCT00005036 | National Cancer Institute (NCI) | Phase 3 |
| Completed | Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu NCT00004074 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer NCT00003873 | National Cancer Institute (NCI) | Phase 3 |
| Completed | Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colo NCT00019760 | National Institutes of Health Clinical Center (CC) | Phase 2 |
| Terminated | Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer NCT00002796 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer NCT00019006 | National Cancer Institute (NCI) | Phase 1 |