| Not Yet Recruiting | Technology-Based Distractions for Minor Procedures NCT06924814 | Stanford University | N/A |
| Not Yet Recruiting | Effect of Music on Pain and Anxiety During Nail Biopsies NCT07518953 | Weill Medical College of Cornell University | N/A |
| Recruiting | Video-based Intervention to Reduce Anxiety in Patients Undergoing Elective PCI NCT07485088 | Tan Tock Seng Hospital | N/A |
| Recruiting | Virtual Reality (VR) for Interventional Radiology (IR) Procedures NCT07427862 | Children's Hospital Los Angeles | — |
| Not Yet Recruiting | The Effect of Two Different Types of Hourglasses on Pain, Fear, and Anxiety NCT07312084 | Hakkari Universitesi | N/A |
| Not Yet Recruiting | Effects of Rain Stick and Musical Egg on Pain, Fear and Anxiety NCT06983093 | Hakkari Universitesi | N/A |
| Recruiting | Oral Surgery Virtual Reality Glasses Study NCT06723158 | Boston University | N/A |
| Enrolling By Invitation | Little NIRVANA for Pediatric Pain and Anxiety NCT06795126 | Nationwide Children's Hospital | N/A |
| Completed | Effects of Liquid Hourglass and Spiky Ball on Pain, Fear, Anxiety and Emotional Manifestations NCT06994637 | Hakkari Universitesi | N/A |
| Completed | Virtual Reality as a Nursing Intervention for Anxiety and Pain in Pediatric Endoscopy NCT07274111 | Mansoura University | N/A |
| Not Yet Recruiting | The Use of Virtual Reality Technology During Oocyte Retrieval for in Vitro Fertilization NCT06733701 | Mount Sinai Hospital, Canada | N/A |
| Completed | The Effects Of Virtual Reality and Stress Ball Application on Pain, Anxiety Levels and Injection Satisfaction NCT07348809 | Tarsus University | N/A |
| Not Yet Recruiting | Pain Elimination and Anxiety Control Through Experiential Virtual Reality NCT06504602 | Children's Hospital Los Angeles | N/A |
| Active Not Recruiting | VR Augmented Human Delivered Integrative Psychotherapy for Colonoscopy Procedural Anxiety and Pain NCT06346171 | Grigore T. Popa University of Medicine and Pharmacy | N/A |
| Completed | "Assessing the Impact of Personalized Music Playlists on Procedural Anxiety and Crown Preparation Performance NCT06856005 | Pakistan Institute of Medical Sciences | N/A |
| Withdrawn | Comparing in Dexmedetomidine With po/pr Midazolam for Procedural Sedation in the Pediatric Emergency Departmen NCT03399838 | Insel Gruppe AG, University Hospital Bern | Phase 4 |
| Recruiting | Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy NCT05895383 | Beth Israel Deaconess Medical Center | Phase 4 |
| Active Not Recruiting | VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures NCT05645224 | Nationwide Children's Hospital | N/A |
| Unknown | Virtual Reality for Anxiety and Pain Management During Oocyte Retrieval in IVF/ICSI Treatment NCT05555498 | Amsterdam UMC, location VUmc | N/A |
| Completed | Evaluating the Feasibility of VR for Pediatric Renal Biopsies NCT05267704 | University of California, San Francisco | N/A |
| Completed | The Effect of Music Therapy and Breathing Exercise on Anxiety and Pain in Patients Undergoing Coronary Angiogr NCT06264960 | Ulku Gunes | N/A |
| Completed | Remimazolam Sedation for Nerve Blocks NCT05415202 | University of Utah | — |
| Unknown | Virtual Reality as a Substitute to Pharmacological Sedation During PICC Placement in Pediatric Patients NCT05275621 | ASST Fatebenefratelli Sacco | N/A |
| Completed | Use of an Adaptive Sensory Environment in Autism Spectrum Disorder (ASD) Patients in the Perioperative Environ NCT04994613 | Dayton Children's Hospital | N/A |
| Completed | Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children NCT04586504 | Columbia University | Phase 1 / Phase 2 |
| Unknown | Nebulized Lidocaine and Intranasal Midazolam for NGT Insertion in Children NCT04571879 | Hamad Medical Corporation | Phase 3 |
| Completed | A Single Blinded Randomized Controlled Trial Testing the Efficacy of a Pediatric Interactive Relational Agent NCT04586569 | Boston Children's Hospital | N/A |
| Completed | Impact of Virtual Reality on Peri-interventional Pain, Anxiety and Distress in a Pediatric Oncology Outpatient NCT06235723 | Hannover Medical School | N/A |
| Completed | The Effect of Dry Heat and Dry Cold Application on Blood Sampling in Children NCT05974319 | Saglik Bilimleri Universitesi | N/A |
| Terminated | The Effect of Music on Colonoscopy (MUSICOL) NCT04628052 | University of Illinois at Chicago | N/A |
| Unknown | Cognitive Behavioral Intervention to Reduce Procedural Anxiety Among Woman With High Risk Pregnancies With Sch NCT04203082 | University of Colorado, Denver | N/A |
| Unknown | Determining the Pharmacogenetic Basis of Non-responsiveness to the Sedative Effects of Dexmedetomidine in Chil NCT04471402 | Hong Kong Children's Hospital | — |
| Completed | Can Virtual Reality Reduce Pain and Anxiety During Blood Draw NCT04449341 | C.R.Darnall Army Medical Center | N/A |
| Completed | Anxiety Reduction During Office Procedural Medicine Using Aromatherapy NCT04260399 | Loyola University | N/A |
| Completed | Pain, Anxiety During Interventional Spine Procedures NCT04257019 | MetroHealth Medical Center | N/A |
| Unknown | Effects of Virtual Reality, Cold-Vibration Due To Intravenous Catheterization on Pain, Fear and Anxiety on Chi NCT05435105 | Akdeniz University | N/A |
| Unknown | Effects of Virtual Reality, External Cold and Vibration to Children During IM Injection on Pain, Fear and Anxi NCT05434832 | Akdeniz University | N/A |
| Unknown | Effect of Virtual Reality Distraction on Procedural Pain for Children and Adolescents in Onco-Hematology Unit. NCT03888690 | Central Hospital, Nancy, France | N/A |
| Unknown | Virtual Reality for Alleviation of Peripheral IV Placement-Associated Discomfort NCT03740607 | Brooke Army Medical Center | N/A |
| Completed | Virtual Reality for Needle Procedures in the Pediatric Emergency Department NCT03750578 | St. Justine's Hospital | N/A |
| Completed | Technology-Based Distractions During Minor Procedures NCT03628989 | Stanford University | N/A |
| Completed | Virtual Reality for Anxiolysis During Laceration Repair in the Pediatric Emergency Room NCT03475901 | Montefiore Medical Center | N/A |
| Completed | The Effect of Cognitive-Behavioral Intervention Package on Procedural Pain and Anxiety in Children NCT06018909 | Aynur Aytekin Ozdemir | N/A |
| Completed | Auditory Intraoperative Stimulation Effects on Pain and Agitation at Awakening (AUDIOPAW) NCT04112979 | IRCCS Burlo Garofolo | N/A |
| Completed | Nonpharmacological Methods for Children in Procedural Pain NCT04421430 | Istanbul Medeniyet University | N/A |
| Completed | Nonpharmacological Methods for Children NCT05070325 | Bandırma Onyedi Eylül University | N/A |
| Completed | Efficacy of VR and Buzzy on Pain and Anxiety NCT05179291 | Bandırma Onyedi Eylül University | N/A |
| Terminated | Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients NCT03043430 | Brooke Army Medical Center | Phase 4 |