| Active Not Recruiting | Exploring the Application of 3D Bioprinting for Personalized Treatment in Primary Liver Cancer With Tumor Micr NCT07437859 | Peking Union Medical College Hospital | — |
| Recruiting | Y-90 Treatment Response Using Transarterial Radioembolization NCT07145801 | Thomas Jefferson University | Phase 2 |
| Recruiting | cfDNA Methylation for Liver Cancer Recurrence Detection NCT07466602 | Wuhan Ammunition Life-tech Co., Ltd | — |
| Recruiting | The Dragon PLC Trial (DRAGON-PLC) NCT06914648 | Maastricht University | N/A |
| Recruiting | Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer NCT06766643 | Tianjin Medical University Cancer Institute and Hospital | Phase 2 |
| Recruiting | Stroke Volume Variation Versus Central Venous Pressure Guidance for Reducing Perioperative Blood Loss During O NCT06905015 | Warangkana Lapisatepun | N/A |
| Recruiting | Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary NCT06486454 | HistoSonics, Inc. | — |
| Recruiting | An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Charact NCT07101237 | Peking Union Medical College Hospital | — |
| Recruiting | Recurrent Liver Cancer: Reconceptualization and Reevaluation NCT06430983 | Nanjing Medical University | — |
| Recruiting | An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer NCT06342414 | City of Hope Medical Center | — |
| Completed | Precision Dietary Intervention Improves Postoperative Energy Intake, Nutritional Status, and Recovery in Patie NCT07349576 | Anhui Provincial Hospital | N/A |
| Unknown | Multi-center Clinical Study on the Decision Tree of Precision Hepatectomy in China Precision Hepatectomy Decis NCT05986383 | Beijing Tsinghua Chang Gung Hospital | — |
| Unknown | MRI-guided Holmium-166 Radioembolization NCT05609448 | Radboud University Medical Center | N/A |
| Active Not Recruiting | Registry on Percutaneous Electrochemotherapy NCT05267080 | Cardiovascular and Interventional Radiological Society of Europe | — |
| Unknown | Polyvinyl Alcohol Embolization Microspheres NCT05770635 | Shanghai Huihe Medical Technology Co., Ltd | N/A |
| Active Not Recruiting | Multi-mode Ablation and Molecular Imaging Multi-omics Study for Digestive-Origin Malignant Liver Tumors NCT06588569 | Fudan University | N/A |
| Completed | Clinical Validation of a Fractional Administration Device for Holmium-166 SIRT NCT05183776 | Radboud University Medical Center | N/A |
| Unknown | Single-cell RNA Sequencing Resolves the Regulatory Role of HBV on the Hepatocellular Carcinoma Immune Microenv NCT05677724 | Fubing Wang | — |
| Unknown | Effect of Food and Formulation on the Pharmacokinetics, Safety, and Tolerability of GNS561 After One Single Do NCT05353894 | Genoscience Pharma | Phase 1 |
| Withdrawn | Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated Primary Liver Cancer NCT05292443 | Geneplus-Beijing Co. Ltd. | — |
| Recruiting | Liver Embolization Approaches for Tumor Management NCT05714124 | IRCCS San Raffaele | — |
| Recruiting | Clinical Study of VG161 in Subjects with Advanced Primary Liver Cancer NCT04806464 | CNBG-Virogin Biotech (Shanghai) Ltd. | Phase 1 |
| Completed | Efficacy of Intravenous Lidocaine on Postoperative Pain and Recovery in Patients Undergoing Hepatectomy NCT04295330 | West China Hospital | N/A |
| Completed | Preoperative Physical Activity Intervention in Patients Before Planned Liver Resection for Cancer (APACHE) NCT03518632 | Célia Turco | N/A |
| Withdrawn | Improving CBCT for Liver IG-SBRT Using Gadoxetate Disodium NCT03215355 | Slawa Cwajna | Phase 4 |
| Unknown | RFA or Surgical Resection Combined With Neo-MASCT for Primary HCC: a Phase II Trial NCT03067493 | Sun Yat-sen University | Phase 2 |
| Unknown | Effect of SAMe Treatment on Recurrence After Radical Treatment of Primary Hepatic Carcinoma NCT03178929 | Beijing Insight Science & Technology Co. Ltd. | N/A |
| Unknown | Chinese Liver Cancer Clinical Survey NCT03161925 | Beijing Insight Science & Technology Co. Ltd. | — |
| Completed | Magnetic Resonance Imaging (MRI) Solely For Liver Stereotactic Body Radiation Therapy (SBRT) NCT02722395 | Duke University | — |
| Unknown | The Effect of Branched-chain Amino Acid (BCAA) on the Progression of Primary Liver Cancer NCT02327819 | Tel-Aviv Sourasky Medical Center | N/A |
| Terminated | A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection NCT01829971 | Mirna Therapeutics, Inc. | Phase 1 |
| Unknown | Primary Liver Cancer Cohort of South China NCT03297255 | Huilian Zhu | — |
| Completed | Role PET Imaging in Response Assessment for Hepatocellular Carcinoma (HCC) NCT01116804 | University Hospital, Ghent | Phase 1 |
| Unknown | Clinical Characteristics of Primary Liver Cancer NCT06325267 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Completed | Efficacy and Significance of Antiviral Therapy for Unresectable Hepatitis B Virus-related Primary Liver Cancer NCT00824707 | Eastern Hepatobiliary Surgery Hospital | N/A |
| Completed | Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms NCT01640522 | University of Pittsburgh | N/A |
| Terminated | Phase III Study of PI-88 in Post-resection Hepatocellular Carcinoma NCT00568308 | Progen Pharmaceuticals | Phase 3 |
| Completed | Evaluation of Preoperative Investigations in Patients With Liver Cancer NCT00408122 | Odense University Hospital | — |
| Completed | Prospective Randomised Study of Doxorubicin in the Treatment of Hepatocellular Carcinoma by Drug-Eluting Bead NCT00261378 | Boston Scientific Corporation | Phase 2 |
| Terminated | Antineoplaston Therapy in Treating Patients With Primary Liver Cancer NCT00003530 | Burzynski Research Institute | Phase 2 |
| Approved For Marketing | TheraSphere® for Treatment of Unresectable Hepatocellular Carcinoma NCT00906984 | University of California, Irvine | — |