Pleural Infection

19 registered clinical trials studyying Pleural Infection — 5 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Intrapleural Alteplase-Tyloxapol vs Intrapleural Alteplase-DNase in Pleural Infection NCT07432373	National University of Malaysia	—
Not Yet Recruiting	Diagnostic Utility of Pleural Infection-specific Multiplex PCR Panel NCT07077096	Chinese University of Hong Kong	—
Recruiting	Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicat NCT06434324	Mayo Clinic	N/A
Recruiting	Trial of Reduced Alteplase Dose for Parapneumonic Effusion (TRAPPE) NCT05766124	Chinese University of Hong Kong	Phase 2 / Phase 3
Recruiting	Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas NCT06427538	Vanderbilt University Medical Center	N/A
Active Not Recruiting	Pleural Fluid Neutrophil Extracellular Traps Exacerbate Disease Severity and Risk of One-year Mortality in Ple NCT07194915	University of Oxford	—
Unknown	Predictors of Outcome in Patients With Pleural Infection at Sohag University Hospital NCT06141174	Sohag University	—
Completed	Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic NCT05903417	National University of Malaysia	N/A
Completed	Fluid Agitation Microbiologic Yield In Pleural Infection Feasibility Study NCT05702580	Alexandria University	N/A
Completed	The Oxford Pleural Infection Endotyping Study NCT06513689	University of Oxford	—
Completed	Antiseptic Irrigation for Pleural Infection NCT04761133	Alexandria University	Phase 1
Completed	Short Versus Long Antibiotic Course for Pleural Infection Management (SLIM Trial) NCT04615286	Alexandria University	N/A
Unknown	Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention NCT05910112	University of Oxford	—
Unknown	Oral Versus Intravenous Antibiotics for the Treatment of Pleural Space Infection: a Randomized Controlled Pilo NCT04301869	St. Joseph's Healthcare Hamilton	N/A
Completed	Pharmacokinetics and Pleural Fluid Penetration of Amoxicillin and Clavulanic Acid in Patients With Pleural Inf NCT04350502	Centre Hospitalier Universitaire, Amiens	N/A
Completed	The Microbiology of Pleural Infection NCT04569110	University of Oxford	—
Completed	Fibrinolysis Compared to Thoracoscopy for Pleural Infection NCT03468933	Tulane University	Phase 4
Completed	Fibrinolysis Compared to Thoracoscopy for Pleural Infection NCT02973139	Beth Israel Deaconess Medical Center	N/A
Completed	Advanced Ultrasound in Pleural Infection NCT02608814	University of Oxford	N/A