| Recruiting | The Impact of Perianal Disease on Patient's Sex Life NCT07519850 | AHEPA University Hospital | — |
| Not Yet Recruiting | Role of MRI in Perianal Fistula NCT07510204 | Sohag University | — |
| Recruiting | Recurrence and Anal Fistula Patient Reported Outcomes Trial NCT07477496 | National and Kapodistrian University of Athens | — |
| Not Yet Recruiting | Comparing Three Surgical Techniques for the Treatment of Transsphincteric Perianal Fistula: (1) Traditional Fi NCT07236047 | Alexandria University | N/A |
| Completed | Procedure-Specific Approach To Minimize Fistulaization of The Perianal Abscess Cavity After Surgical Drainage NCT06527833 | Suez Canal University | N/A |
| Completed | Diagnostic Value of Recto-perineal Ultrasound in Perianal Fistula NCT06314945 | Zagazig University | — |
| Terminated | Study of ExoFlo for the Treatment of Perianal Fistulas NCT05836883 | Direct Biologics, LLC | Phase 1 / Phase 2 |
| Unknown | Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia NCT05990569 | Nepal Mediciti Hospital | N/A |
| Recruiting | Semiflex Assisted Vacuum Therapy for Perianal Abscesses/Sinuses and Fistula: a Pilot Study NCT06446635 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Unknown | Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-ric NCT05709717 | Kantonsspital Winterthur KSW | — |
| Unknown | Comparative Accuracy of Transperineal Ultrasound (TPUS) Versus Magnetic Resonance Imaging (MRI) for the Assess NCT05721794 | IRCCS San Raffaele | — |
| Completed | A Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease NCT05626023 | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | Phase 1 / Phase 2 |
| Unknown | Antibiotic Treatment foLlowing Surgical drAinage of Perianal abScess; the ATLAS Trial NCT05385887 | dr. IJM Han-Geurts | N/A |
| Completed | Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial NCT04549311 | Sunnybrook Health Sciences Centre | Phase 3 |
| Active Not Recruiting | Seeded Cells on Matrix Plug Treating Crohn's Perianal Fistulas (STOMP-II) NCT04847739 | Avobis Bio, LLC | Phase 2 |
| Withdrawn | Treatment of Lower Transsphincteric Perianal Fistula: Fistulotomy With Marsupialization vs Open Wound NCT04722965 | Consorci Sanitari de l'Alt Penedès i Garraf | N/A |
| Terminated | Mesenchymal Stem Cells for the Treatment of Perianal Fistulizing Crohn's Disease NCT04519671 | Anthony Lembo | Phase 1 / Phase 2 |
| Completed | Perianal Fistula (PAF) Validation and Burden of Illness Study NCT03981939 | Takeda | — |
| Unknown | Tight Control Management in Perianal Crohn's Disease NCT03861689 | Chinese University of Hong Kong | N/A |
| Unknown | Permacol Paste in Perianal Crohn's Disease NCT03776825 | Istituto Clinico Humanitas | — |
| Unknown | Perianal Fistula Treatment With Autologous Adipose Tissue Injection NCT03913910 | Azienda Ospedaliero, Universitaria Pisana | — |
| Unknown | Effects of Sodium Pentaborat Based Gel on Perianal Benign Diseases NCT03780998 | SB Istanbul Education and Research Hospital | — |
| Unknown | Treatment of Perianal Disease Using Adipose-derived Stem Cells NCT03913572 | University of California, San Diego | — |
| Completed | Transsphincteric Fistula Management Using LIFT and MAF NCT06616662 | Zagazig University | — |
| Completed | Perianal Nerval Block in Proctological Interventions NCT03405922 | University Hospital, Basel, Switzerland | Phase 4 |
| Completed | Comparison of Prolene Thread Seton Vs Silk Thread Seton for the Treatment of Perianal Fistula NCT03763981 | Services Hospital, Lahore | N/A |
| Completed | Re-treatment From a Phase I Study of MSC-AFP in Patients With Perianal Fistulas NCT03209700 | William A. Faubion, M.D. | Phase 1 |
| Withdrawn | Phase 1 Crohn's Pediatric Sub-study of MSC AFP NCT03014219 | William A. Faubion, M.D. | Phase 1 |
| Unknown | Fistulodesis Pilot Study for Closure of Perianal Fistulae NCT03322488 | University of Zurich | N/A |
| Unknown | MR Assessment of Perianal Crohn's Disease NCT03325582 | University of Nottingham | — |
| Completed | TIPS Microspheres for Perianal Fistula NCT03707769 | University College, London | N/A |
| Unknown | Adding Ketamine to Low Dose Bupivacaine in Saddle Block for Perianal Surgery NCT03264430 | Esam Eldin Mohamed Abdalla | EARLY_Phase 1 |
| Completed | SuperSeton Pilot Studie NCT03654482 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Micro-fragmented Adipose Tissue and Complex Crohns' Anal Fistulas NCT03555773 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | N/A |
| Completed | Stem Cell Fistula Plug in Cryptoglandular Perianal Fistulas (MSC-AFP) NCT02589119 | Mayo Clinic | Phase 1 |
| Completed | Adipose Tissue in Crohn´s Disease Fistulas NCT03803917 | Lilli Lundby | N/A |
| Completed | Adipose Derived Mesenchymal Stem Cell Characteristics in Anal Fistulas NCT04834609 | University of Aarhus | N/A |
| Unknown | Autologous Adipose-derived Stem Cells (ASCs) for the Treatment of Perianal Fistula in Crohn Disease: A Pilot S NCT02403232 | Papa Giovanni XXIII Hospital | Phase 2 |
| Completed | Stem Cell Therapy: a Compassionate Use Program in Perianal Fistula NCT03726255 | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | — |
| Completed | Surgical Closure vs Anti-TNF in the Treatment of Perianal Fistulas in Crohn's Disease (PISA-II): a Comprehensi NCT06441526 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 3 |
| Terminated | Follow-up Study of Autologous Adipose-derived Stem Cells (ANTG-ASC) for the Complex Fistula (ANTG-ASC-211) NCT01623453 | Anterogen Co., Ltd. | — |
| Completed | Anal Fistula Treatment Outcome - Collagen Plug Versus Advancement Flap Surgery NCT01021774 | University Hospital, Akershus | N/A |
| Completed | Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease NCT00972088 | Bikkur Holim Hospital | N/A |