Clinical Trials Directory

Trials / Conditions / Locally Advanced Malignant Solid Neoplasm

Locally Advanced Malignant Solid Neoplasm

30 registered clinical trials studyying Locally Advanced Malignant Solid Neoplasm10 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingAdoption of Audio Recording in the Outpatient Supportive Care Center
NCT04871477
M.D. Anderson Cancer Center
WithdrawnSTIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Col
NCT06626256
City of Hope Medical CenterPhase 1
RecruitingTesting the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in P
NCT06364410
National Cancer Institute (NCI)Phase 1
CompletedDesign and Testing of a Web-Based Tool for the Improvement of End-of-Life Planning in Patients With Advanced C
NCT05564468
Fred Hutchinson Cancer CenterN/A
SuspendedStudy of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Trea
NCT05554380
National Cancer Institute (NCI)Phase 2
RecruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumo
NCT05564377
National Cancer Institute (NCI)Phase 2
WithdrawnAlpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcino
NCT05472220
Pamela MunsterPhase 1
RecruitingPersonalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Soli
NCT05269381
Mayo ClinicPhase 1 / Phase 2
WithdrawnBAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors
NCT05010096
M.D. Anderson Cancer CenterPhase 1
SuspendedAssessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supporti
NCT05091632
M.D. Anderson Cancer Center
RecruitingLarotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors
NCT04879121
M.D. Anderson Cancer CenterPhase 2
TerminatedCMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma
NCT04387071
University of Southern CaliforniaPhase 1 / Phase 2
CompletedDistress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced Can
NCT05058339
M.D. Anderson Cancer Center
RecruitingMeasuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
NCT04550494
National Cancer Institute (NCI)Phase 2
TerminatedPevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Sol
NCT04800627
M.D. Anderson Cancer CenterPhase 1 / Phase 2
CompletedIntegrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer
NCT04697524
University of California, San FranciscoN/A
RecruitingAvapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Sol
NCT04771520
M.D. Anderson Cancer CenterPhase 2
CompletedPLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning
NCT04889144
Fred Hutchinson Cancer CenterN/A
WithdrawnTesting the Safety of CB-5339 in Patients With Cancer
NCT04372641
National Cancer Institute (NCI)Phase 1
Active Not RecruitingTesting the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Me
NCT04068194
National Cancer Institute (NCI)Phase 1 / Phase 2
CompletedPembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers
NCT04082572
M.D. Anderson Cancer CenterPhase 2
RecruitingDurvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial
NCT03907475
National Cancer Institute (NCI)Phase 2
WithdrawnBrigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Ca
NCT03868423
Sameek RoychowdhuryPhase 2
Active Not RecruitingTesting AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2
NCT03284385
National Cancer Institute (NCI)Phase 2
RecruitingCeralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors
NCT03682289
Rahul AggarwalPhase 2
Active Not RecruitingPhysical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Locally Ad
NCT03583255
M.D. Anderson Cancer CenterPhase 2
Active Not RecruitingCeritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-I
NCT02321501
M.D. Anderson Cancer CenterPhase 1
CompletedTesting the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medication
NCT02595866
National Cancer Institute (NCI)Phase 1
RecruitingEvaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types
NCT06075524
Mayo Clinic
CompletedUprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
NCT01902173
National Cancer Institute (NCI)Phase 1 / Phase 2