Trials / Conditions / Leptomeningeal Metastases

Leptomeningeal Metastases

20 registered clinical trials studyying Leptomeningeal Metastases — 6 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative B NCT06462092	Guangzhou Medical University	Phase 1 / Phase 2
Not Yet Recruiting	High-Dose Firmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed in the Treatment of EGFR-Mutated NCT06971406	Qiming Wang	Phase 2
Not Yet Recruiting	Cerebrospinal Fluid Cytology-guided Intrathecal Chemo-holiday Therapy for EGFR-positive NSCLC Leptomeningeal M NCT06861218	Zhejiang Cancer Hospital	Phase 2
Not Yet Recruiting	Ivonescimab Combined With Chemotherapy for the Treatment of Leptomeningeal Metastases Failed to EGFR-TKIs NCT06766591	Jiangsu Province Nanjing Brain Hospital	N/A
Recruiting	Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for E NCT06728865	Li-kun Chen	Phase 2
Unknown	ANG1005 in Leptomeningeal Disease From Breast Cancer NCT03613181	Angiochem Inc	Phase 3
Completed	Intrathecal Pemetrexed for Leptomeningeal Metastasis NCT05289908	The First Hospital of Jilin University	Phase 1 / Phase 2
Recruiting	A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis NCT05184816	Memorial Sloan Kettering Cancer Center	Phase 1
Completed	Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From NCT04343573	Memorial Sloan Kettering Cancer Center	Phase 2
Completed	Avelumab With Radiotherapy in Patients With Leptomeningeal Disease NCT03719768	H. Lee Moffitt Cancer Center and Research Institute	Phase 1
Terminated	BATs in Patients With Breast Cancer and Leptomeningeal Metastases NCT03661424	University of Virginia	Phase 1
Terminated	131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases NCT03275402	Y-mAbs Therapeutics	Phase 2 / Phase 3
Completed	Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases NCT03520504	Memorial Sloan Kettering Cancer Center	Phase 1
Completed	Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer NCT03101579	The First Hospital of Jilin University	Phase 1
Completed	Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases NCT02616393	Kadmon Corporation, LLC	Phase 2
Withdrawn	Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease NCT01438021	City of Hope Medical Center	N/A
Completed	Interest of Intrathecal Chemotherapy With Liposomal Cytarabine (DepoCyte®) in Meningeal Metastasis of Breast C NCT01645839	Centre Oscar Lambret	Phase 3
Completed	Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases Fr NCT00992602	University of Washington	Phase 2
Completed	Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatmen NCT00005811	National Cancer Institute (NCI)	Phase 2
Terminated	Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma NCT00005812	Dartmouth-Hitchcock Medical Center	Phase 2