| Recruiting | Regulation of Brain Glucose Metabolism in Type 1 Diabetes NCT05317455 | Yale University | EARLY_Phase 1 |
| Unknown | Hypoglycemia Awareness Study in Diabetes Type 1 NCT05620927 | Poznan University of Medical Sciences | — |
| Completed | Restoration of Hypoglycemia Awareness With Home-based High Intensity Interval Training NCT04825366 | Institut de Recherches Cliniques de Montreal | N/A |
| Completed | Maximising Time With a Normal Blood Glucose to Restore the Glucagon Response in Type 1 Diabetes NCT04614168 | University of Edinburgh | N/A |
| Terminated | Continuous Glucose Monitoring Initiation at Hospital Discharge NCT04854135 | Washington University School of Medicine | N/A |
| Completed | Hypo-METRICS: Hypoglycaemia - Measurement, ThResholds and ImpaCtS NCT04304963 | King's College London | — |
| Terminated | CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia NCT04452396 | Barts & The London NHS Trust | N/A |
| Recruiting | Restoration of Hypoglycemia Awareness With Metoclopramide NCT03970720 | Simon Fisher | Phase 2 |
| Terminated | Carvedilol in Treating Hypoglycemia Unawareness NCT03538015 | Owen Chan, PhD | Phase 2 |
| Terminated | Novel Approach for the Prevention of Hypoglycemia Associated Autonomic Failure (HAAF) NCT03608163 | Albert Einstein College of Medicine | Phase 4 |
| Terminated | Assessment of the Impact of Real-Time Continuous Glucose Monitoring on People Presenting With Severe Hypoglyca NCT03748433 | Imperial College London | N/A |
| Completed | Effect of Dapagliflozin on IAH in T1DM NCT03556033 | Radboud University Medical Center | Phase 2 |
| Completed | Prevention Through Intervention: Telehealth Solution to Deter 911 Calls Due to Hypoglycemia NCT03665870 | University of Alabama at Birmingham | N/A |
| Terminated | Amitriptyline in Treating Hypoglycemia NCT03591458 | University of Utah | Phase 2 |
| Unknown | The Effect Lactate Administration on Cerebral Blood Flow During Hypoglycemia NCT03730909 | Radboud University Medical Center | N/A |
| Terminated | Glucagon Infusion in T1D Patients With Recurrent Severe Hypoglycemia: Effects on Counter-Regulatory Responses NCT03490942 | Xeris Pharmaceuticals | Phase 2 |
| Completed | Hybrid Closed Loop Insulin Delivery System in Hypoglycemia NCT03215914 | University of Pennsylvania | N/A |
| Active Not Recruiting | Adrenergic System in Islet Transplantation NCT03079921 | University of Pennsylvania | EARLY_Phase 1 |
| Terminated | Intra-nasal Naloxone for Treatment of Impaired Awareness of Hypoglycemia NCT02700048 | University of Minnesota | Phase 1 / Phase 2 |
| Completed | A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of NCT02206152 | University of Minnesota | Phase 1 / Phase 2 |
| Completed | The Role of Endogenous Lactate in Brain Preservation and Counterregulatory Defenses Against Hypoglycemia NCT02308293 | Radboud University Medical Center | N/A |
| Completed | Allogeneic Islet Cells Transplanted Onto the Omentum NCT02213003 | Rodolfo Alejandro | Phase 1 / Phase 2 |
| Completed | The Effect of Hypoglycaemia on Brain Lactate Accumulation and Cerebral Blood Flow NCT02146404 | Radboud University Medical Center | N/A |
| Completed | The Effects of RT-CGM on Glycemia and QoL in Patients With T1DM and IHA NCT01787903 | Amsterdam UMC, location VUmc | N/A |
| Completed | Glucose Counterregulation in Long Standing Type 1 Diabetes NCT01474889 | University of Pennsylvania | N/A |
| Completed | Naltrexone and Hypoglycemia in Type 1 Diabetes NCT01053078 | University of Minnesota | Phase 1 / Phase 2 |
| Completed | Measurement of Glucose Metabolism in Humans Using Magnetic Resonance at 4 Tesla. Substudy: Hypoglycemia Unawar NCT00793741 | University of Minnesota | — |
| Completed | The Effect of Antecedent Hypoglycaemia on β2-adrenergic Sensitivity NCT00160056 | Radboud University Medical Center | N/A |
| Completed | Cerebral Responses to Insulin Induced Hypoglycemia NCT02747680 | University of Minnesota | N/A |