| Not Yet Recruiting | Phase I Clinical Trial of Enterovirus Type71 - Coxsackievirus Type A16 Bivalent Vaccine NCT07326878 | Institute of Medical Biology, Chinese Academy of Medical Sciences | Phase 1 |
| Enrolling By Invitation | Study on the Persistence of Immunity Following EV71 Vaccination NCT07144202 | Institute of Medical Biology, Chinese Academy of Medical Sciences | — |
| Recruiting | Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial NCT06699433 | Southern Medical University, China | N/A |
| Unknown | Active Case Finding of Clinical Hand Foot Mouth Disease in Children Aged 6 Months Old to 18 Years Old in Indon NCT06251219 | Sinovac Biotech Co., Ltd | — |
| Recruiting | Lot-to-lot Consistency Study of Three Commercial Batches of Enterovirus 71 Vaccine NCT06146088 | Institute of Medical Biology, Chinese Academy of Medical Sciences | Phase 4 |
| Active Not Recruiting | Inactivated Bivalent Enterovirus Vaccine (Vero Cell) Phase I/II Clinical Trial NCT06063057 | Sinovac Biotech Co., Ltd | Phase 1 / Phase 2 |
| Recruiting | Surveillance of HFMD in Pediatric Outpatients NCT06263439 | University Hospital, Clermont-Ferrand | — |
| Completed | A Serosurvey Study of Hand, Foot, and Mouth Disease in Indonesia NCT05637229 | Sinovac Biotech Co., Ltd | — |
| Unknown | An Immunity Persistence Study of Enterovirus 71 Inactivated Vaccine (Vero Cell) NCT05397587 | Sinovac Biotech Co., Ltd | Phase 4 |
| Unknown | Safety Observation of Enterovirus 71 Inactivated Vaccine (Vero Cell) Combined Immunization in Shanghai NCT05166044 | Sinovac Biotech Co., Ltd | — |
| Unknown | Safety and Immunogenicity of High-dose IN-B001 in Healthy Subjects NCT04637919 | HK inno.N Corporation | Phase 1 |
| Completed | Safety & Immunogenicity of Enterovirus Type 71 Vaccine in Healthy Adults and Children 6-71months NCT04467541 | International Centre for Diarrhoeal Disease Research, Bangladesh | Phase 1 / Phase 2 |
| Unknown | Safety and Immunogenicity of CJ-40010 in Healthy Subjects NCT04182932 | HK inno.N Corporation | Phase 1 |
| Completed | The Immunogenicity and Safety of the Vaccination of Inactivated Enterovirus 71 Vaccine and Seasonal Influenza NCT04133584 | Zhejiang Provincial Center for Disease Control and Prevention | Phase 4 |
| Completed | Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With Expanded Programme on Immunizatio NCT04111432 | Sinovac Biotech Co., Ltd | Phase 4 |
| Completed | Hand, Foot, and Mouth Disease: Could EPs®7630 be a Treatment Option NCT06353477 | Eskisehir Osmangazi University | Phase 2 / Phase 3 |
| Completed | Efficacy Evaluation for Inactivated Vaccine (Vero Cell) Against EV71 NCT03582761 | Jiangsu Province Centers for Disease Control and Prevention | Phase 4 |
| Completed | Immunity and Safety of Inactivated Enterovirus 71 Vaccine Post-marketing Among Children Aged 6-35 Months in Ch NCT03893747 | Jiangsu Province Centers for Disease Control and Prevention | Phase 4 |
| Completed | Efficacy Trial of a Commercial EV71 Vaccine NCT03903926 | Sinovac Biotech Co., Ltd | Phase 4 |
| Completed | Clinical Trial of Enterovirus 71（EV71） Inactivated Vaccine in Children Aged 36-71 Months NCT03909074 | Sinovac Biotech Co., Ltd | Phase 3 |
| Unknown | Study to Evaluate the Tolerance and Pharmacokinetics of Suramin Sodium NCT03804749 | First Affiliated Hospital of Zhejiang University | Phase 1 |
| Completed | Immunogenicity and Safety of Two Different Commercial EV71 Vaccines NCT03873740 | Sinovac Biotech Co., Ltd | Phase 4 |
| Unknown | Immunogenicity of the Inactivated EV71 Vaccine Combined With Hepatitis B and Group A Meningococcal Vaccine NCT06209398 | Jiangsu Province Centers for Disease Control and Prevention | Phase 4 |
| Completed | Sucralfate to Improve Oral Intake in Children With Infectious Oral Ulcers: a Randomized, Double-blind, Placebo NCT03241030 | University of Texas at Austin | Phase 2 |
| Completed | Phase IV Clinical Trial, Immunogenicity and Safety of EV71 Vaccine NCT03278132 | Sinovac Biotech Co., Ltd | Phase 4 |
| Completed | Five-year Immune Persistence Study of Inactivated Enterovirus Type 71 (EV71) Vaccine NCT03281174 | Sinovac Biotech Co., Ltd | — |
| Completed | Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With EPI Vaccines NCT03274102 | Sinovac Biotech Co., Ltd | Phase 4 |
| Unknown | Safety, Three Batches Consistency and Immunity Duration of the Post-marketing Inactivated Enterovirus Type 71 NCT02889497 | Beijing Chaoyang District Centre for Disease Control and Prevention | Phase 4 |
| Completed | Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam NCT01940250 | Oxford University Clinical Research Unit, Vietnam | Phase 2 |
| Completed | Neurodevelopment Outcomes Following Severe Hand Foot and Mouth Disease in Vietnam NCT02066714 | Oxford University Clinical Research Unit, Vietnam | — |
| Completed | A Follow-up Study for a Phase III, Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine NCT02001233 | Sinovac Biotech Co., Ltd | — |
| Completed | Immunogenicity and Safety of Three Consecutive Lots of a New Inactivated Enterovirus Type 71 (EV71) Vaccine NCT01636245 | Sinovac Biotech Co., Ltd | Phase 3 |
| Completed | An Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine NCT01507857 | Sinovac Biotech Co., Ltd | Phase 3 |
| Completed | A Clinical Trial to Assess the Efficacy and Safety of an Inactivated Vaccine (Vero Cell) Against EV71 in Chine NCT01508247 | Jiangsu Province Centers for Disease Control and Prevention | Phase 3 |
| Completed | Safety and Immunogenicity Study of an Inactivated Vaccine Against Hand, Foot and Mouth Disease Caused by Enter NCT01376479 | Inviragen Inc. | Phase 1 |
| Completed | Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double NCT01769794 | China Academy of Chinese Medical Sciences | N/A |
| Completed | A Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants NCT01313715 | Jiangsu Province Centers for Disease Control and Prevention | Phase 1 |
| Completed | A Safety Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Adults, Children and Infant NCT01391494 | Institute of Medical Biology, Chinese Academy of Medical Sciences | Phase 1 |
| Completed | A Clinical Trial for Inactivated Vaccine(Vero Cell) Against EV71 in Chinese Healthy Young Adults and Children NCT01267903 | Jiangsu Province Centers for Disease Control and Prevention | Phase 1 |
| Completed | Study on Dynamic Changes of the Maternal Anti-EV71 and Anti-CVA16 Antibody Levels in Infants and Young Childre NCT01255124 | Jiangsu Province Centers for Disease Control and Prevention | — |
| Unknown | A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type NCT01182025 | The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine | N/A |
| Completed | A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of NCT01182532 | The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine | N/A |
| Unknown | A Multi-Center Clinical Trial To Evaluate Chinese Herbal Medicines in the Treatment of Severe Hand-foot-mouth NCT01145664 | Beijing YouAn Hospital | N/A |
| Completed | Effectiveness and Safety of Chinese Medicine to Treat Hand, Foot, and Mouth Disease NCT01554930 | Jiangxi Qingfeng Pharmaceutical Co. Ltd. | N/A |
| Unknown | A Clinical Trial To Evaluate Reduning Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease NCT01175915 | Jiangsu Kanion Pharmaceutical Co., Ltd | N/A |