| Recruiting | Er:YAG Laser Combined With Vaginal Estriol for Genitourinary Syndrome of Menopause NCT06873971 | University of Nove de Julho | N/A |
| Not Yet Recruiting | Impact of Oral Supplementation With Bioactive Collagen Peptides and Other Functional Ingredients NCT07151482 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Effectiveness of a Telerehabilitation Program for Improving Sexual Function and Reducing Pain in Menopausal Wo NCT06710002 | Instituto Médico Tecnológico SL | N/A |
| Not Yet Recruiting | Intravaginal Negative Pressure Medical Device for Treatment of Genitourinary Syndrome of Menopause (GSM) NCT06768073 | AVeta Medical | N/A |
| Not Yet Recruiting | Difference in Serum Estrogen Level Based on Methods of Vaginal Estrogen Application (fingertip Vs Applicator U NCT06808347 | Walter Reed National Military Medical Center | Phase 4 |
| Recruiting | Vaginal CO2 Laser Therapy for Genitourinary Syndrome in Breast Cancer Survivors NCT06007027 | University of Aarhus | N/A |
| Not Yet Recruiting | The Efficacy of Topical Vaginal Oxytocin Gel in Postmenopausal Women With Vulvovaginal Atrophy NCT06514586 | Oxagon | Phase 3 |
| Recruiting | Combination of the Vaginal Laser With a Moisturizing and Repairing Niosomal Gel in the Treatment of Genitourin NCT06508788 | Hospital Universitari de Bellvitge | — |
| Recruiting | Efficacy of the Use of Cellular Matrix/ A-CP-HA Kit NCT06425978 | Fundación Santiago Dexeus Font | Phase 4 |
| Enrolling By Invitation | Vaginal Ecosystem and Network in the United States Study NCT06472765 | Vaginal Biome Science | — |
| Active Not Recruiting | Efficacy of Non-Ablative Radiofrequency on Vaginal and Sexual Health in Postmenopausal Women NCT06925139 | University of Castilla-La Mancha | N/A |
| Active Not Recruiting | PRP Injections for Genitourinary Syndrome of Menopause NCT06028009 | Medstar Health Research Institute | N/A |
| Recruiting | Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assesse NCT06962345 | Mucosa Innovations, S.L. | N/A |
| Unknown | Vaginal Hyaluronic Acid, Arginine and Liposome Gel Versus Vaginal Lubricant in Postmenopausal Women With Genit NCT06176820 | Sarawak General Hospital | Phase 2 / Phase 3 |
| Completed | Changes in Neighbouring Microbiota in Genitourinary Syndrome NCT06633705 | Koc University Hospital | Phase 4 |
| Unknown | Comparison of Vaginal Hyaluronic Acid Treatment Over Autologous Platelet Rich Plasma Treatment for Genitourina NCT05571527 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Recruiting | VALOR: Vaginal Atrophy & Long-term Observation of Recovery NCT05953090 | Stratpharma AG | N/A |
| Recruiting | Concomitant Treatment with Topical Hyaluronic Acid and High Concentration Oxygen Therapy (Vaginal Natural Oxyg NCT06879938 | Fondazione IRCCS Policlinico San Matteo di Pavia | N/A |
| Active Not Recruiting | RCT Comparing Intravaginal Laser Therapy to Sham in Post-menopausal Women with Recurrent Urinary Tract Infecti NCT06124820 | King's College Hospital NHS Trust | N/A |
| Active Not Recruiting | A Novel Therapy for Breast Cancer Survivors With Genitourinary Syndrome of Menopause NCT05812924 | University of Miami | Phase 2 |
| Recruiting | Non-ablative Diode Laser Therapy for Genitourinary Syndrome of Menopause: A Prospective Study on Efficacy, Saf NCT06503003 | University of Cagliari | — |
| Recruiting | Vaginal Changes After CO2 Laser NCT06691178 | University of California, Irvine | N/A |
| Recruiting | Silicone Gel vs. Estrogen Vaginal Cream for the Management of Genitourinary Syndrome of Menopause NCT05672901 | Stratpharma AG | N/A |
| Completed | Effects of Pelvic Floor Exercise Training in Postmenopausal Genitourinary Syndrome NCT06034483 | Hacettepe University | N/A |
| Recruiting | Use of Fractional CO2 Laser Versus Erbium:YAG Laser for the Treatment of GSM in Patients Using Aromatase Inhib NCT05713435 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Vulvovaginal Atrophy Questionnaire (VVAQ): Psychometric Validation of a Novel PROM NCT04746456 | Massachusetts General Hospital | — |
| Terminated | The Outcome of Chinese Women With Genitourinary Syndrome of Menopause Treated With Vaginal Dehydroepiandroster NCT05434351 | Chinese University of Hong Kong | — |
| Unknown | Laser Therapy for Treatment of Genitourinary Syndrome of Menopause (GSM) in Postmenopausal Women NCT05305209 | University of Malaga | N/A |
| Completed | Natural Topical Treatment for Vulvar and Vaginal Atrophy NCT05871255 | Dr. Amjad Khan | — |
| Completed | Clinical and Cyto-histological Evaluation of Fractional CO2 Laser Treatment on Genito-Urinary Syndromes of Men NCT05151380 | Hopital Nord Franche-Comte | N/A |
| Unknown | Menopausal Vaginal Microbiome NCT05122065 | FemTec Health Inc. | — |
| Completed | Zinc Containing Vaginal Topical " Suppository " NCT05453227 | Egymedicalpedia | Phase 1 / Phase 2 |
| Completed | The Ultrasonographic Assessment of Efficacy of Injectable Hyaluronic Acid for Genitourinary Syndrome of Menopa NCT05561972 | Maltepe University | N/A |
| Completed | Effects of Ospemifene on Brain Activation Patterns in Women With Sexual Interest-arousal Disorders NCT04677491 | Hospital Clinic of Barcelona | Phase 4 |
| Completed | The Effect of Counseling Based on the Roy Adaptation Model on Sexual Life and Quality of Life in Menopause NCT06605742 | Istanbul University | N/A |
| Withdrawn | MonaLisa Laser Intervention for Post-Menopausal Breast Cancer Patients: A SHE CAN Study NCT04606550 | Mount Sinai Hospital, Canada | N/A |
| Completed | Vaginal Biorevitalization With Polydeoxyribonucleotides for the Improvement of the Genitourinary Syndrome of M NCT05464654 | Hospital Regional 1o de Octubre | N/A |
| Completed | Assessment of the Efficacy of Injectable Hyaluronic Acid for Genitourinary Syndrome of Menopause NCT05559996 | Maltepe University | N/A |
| Completed | Ultrasonic Evaluation of Carbon Dioxide Laser Effects on Patients With Genitourinary Syndrome NCT06142695 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Local DHEA and Estradiol on Dyspareunia in Postmenopausal Women NCT05586711 | Angelica Lindén Hirschberg | Phase 4 |
| Unknown | Sexual and Vaginal Health in Breast Cancer Women Receiving Aromatase Inhibitors Before and After CO2 Laser The NCT04619485 | Hospital Clinic of Barcelona | N/A |
| Completed | Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Bre NCT04535323 | Mayo Clinic | Phase 1 |
| Completed | Vaginal Prasterone In Vaginal Atrophy In Breast Cancer Survivors NCT04705883 | Hospital Clinic of Barcelona | Phase 4 |
| Active Not Recruiting | Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy NCT04737616 | University of California, Irvine | N/A |
| Completed | Management of Cancer Therapy Related Vulvovaginal Atrophy NCT05782920 | Alexandria University | N/A |
| Unknown | Examining Effects of Intrarosa in Women With Genitourinary Syndrome of Menopause/Vulvovaginal Atrophy NCT03782480 | Center for Vulvovaginal Disorders | Phase 3 |
| Terminated | New Non-Hormonal Treatment by Radiofrequency for Vulvo-Vaginal Atrophy NCT03857893 | Serge Rozenberg | N/A |
| Completed | CO2 Laser Therapy for the Treatment of GSM in Patients With Breast Cancer NCT04517370 | Hadassah Medical Organization | N/A |
| Unknown | Vaginal Laser Therapy in Breast Cancer Survivors NCT03738605 | National and Kapodistrian University of Athens | N/A |
| Completed | RCT of Laser Therapy for GSM NCT03288883 | King's College Hospital NHS Trust | N/A |
| Recruiting | Radiofrequency Non-ablative in the Treatment of Genitourinary Syndrome of Menopause NCT03506594 | Centro de Atenção ao Assoalho Pélvico | N/A |
| Completed | Efficacy and Safety of the Neodymium Laser in Treatment of Urogenital Tract Diseases in Women NCT05251220 | 1st Federal Budgetary Healthcare Institution Volga District Medical Center | — |
| Completed | Multi-polar RF and PEMF for Treatment of Vulvovaginal Atrophy NCT04607798 | Venus Concept | N/A |
| Completed | MonaLisa Touch Randomized Double-Blind Placebo Controlled Study NCT03331328 | Michigan Institution of Women's Health PC | N/A |