| Recruiting | Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hyster NCT06969326 | Women and Infants Hospital of Rhode Island | Phase 3 |
| Recruiting | Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Ge NCT07147166 | University of California, San Francisco | N/A |
| Completed | Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria NCT05903911 | University of Wisconsin, Madison | N/A |
| Enrolling By Invitation | MaPGAS Decision Making NCT06565663 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | Understanding Perceived Access and Receipt of Gender-affirming Treatments Among Transgender Veterans NCT06615401 | VA Office of Research and Development | — |
| Recruiting | Sexual Functioning After Erection Prosthesis Placement in Post Phalloplasty Transgender Persons NCT06639776 | University Hospital, Ghent | — |
| Recruiting | Erectile Aid Use in Post-phalloplasty and Post-metoidioplasty Transgender Patients NCT06639763 | University Hospital, Ghent | — |
| Recruiting | Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering from Gender Dysphoria NCT06351501 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria NCT05884307 | University of Wisconsin, Madison | N/A |
| Recruiting | Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty NCT06439290 | University Ghent | N/A |
| Completed | Effects of Gender-affirming Hormone Therapy on Transgender People NCT06022562 | National Taiwan University | — |
| Enrolling By Invitation | Polyethylene-glycol Assisted Nerve Repair in Phalloplasty NCT05897086 | Vanderbilt University Medical Center | Phase 2 / Phase 3 |
| Recruiting | Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients. NCT05883553 | University Hospital, Ghent | N/A |
| Not Yet Recruiting | Evaluation of the Variation in Quality of Life During Medical Transition for Transgender People. NCT05273112 | University Hospital, Lille | — |
| Recruiting | Early Mental Response - The EMRE Study NCT05649605 | Karolinska University Hospital | N/A |
| Recruiting | Gender-Affirming Hormone Therapy and Its Impact on Myocardial Mass and Cardiac Function, Heart, Liver and Panc NCT06291675 | Medical University of Vienna | — |
| Terminated | Comparison of PKs of 17-Beta-Estradiol Via Sublingual Placement Versus Swallowing in Male-to-Female Transgende NCT05428215 | MaineHealth | Phase 4 |
| Not Yet Recruiting | Sex Hormone Overdose and Misuse in Chinese Transgender and Gender Non-conforming Population NCT05583058 | Xiamen University | — |
| Completed | Sleep and IR in Transgender Adolescents NCT05489159 | Duke University | — |
| Unknown | Gynaecological Gender-affirming Surgeries NCT06098781 | Amsterdam UMC, location VUmc | — |
| Completed | Internet-delivered Treatment for Transgender Individuals With Co-occurring Mental Health Problems NCT05534763 | Karolinska Institutet | N/A |
| Recruiting | Effect of Nitropaste in Chest Masculinizing Surgery NCT06428669 | University of Virginia | Phase 4 |
| Completed | Acoustic and Perceptual Effects of Intonation Training in Gender Diverse People NCT05204732 | University Ghent | N/A |
| Completed | Investigation of the Perceptual and Acoustic Voice in Trans Man NCT05166083 | Hacettepe University | — |
| Completed | Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women NCT04283656 | Thomas Jefferson University | Phase 1 |
| Recruiting | Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients NCT04979338 | Cedars-Sinai Medical Center | Phase 3 |
| Recruiting | Patient Reported Outcome on Genital Sensitivity and Sexual Function After Genital Gender Affirming Surgery NCT04993469 | University Hospital, Ghent | N/A |
| Recruiting | Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth NCT04596592 | University of Colorado, Denver | — |
| Recruiting | Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants NCT05097820 | University Hospital, Ghent | — |
| Withdrawn | Developmental Correlates and Hormone Therapy Effects in Gender Dysphoria NCT04309760 | Hôpital le Vinatier | N/A |
| Unknown | Transition in Transgender NCT04736797 | RWTH Aachen University | — |
| Unknown | Gender Dysphoria in Children and Adolescents : Parents' Perspectives NCT04160364 | Central Hospital, Nancy, France | — |
| Unknown | Gender Dysphoria and Transition NCT04265885 | Central Hospital, Nancy, France | — |
| Unknown | Gender Dysphoria: Epidemiological Data NCT04573127 | Central Hospital, Nancy, France | — |
| Unknown | Metabolic Consequences of Cross-sex Hormonal Treatment NCT04508231 | Central Hospital, Nancy, France | — |
| Unknown | Demographic Characteristics and Psychosocial Health of Transgender People NCT04554849 | Central Hospital, Nancy, France | — |
| Active Not Recruiting | Ovarian Tissue Cryopreservation in the Setting of Gender-affirming Therapy NCT05863676 | University of Pittsburgh | — |
| Completed | The Effect of Pectoral Blocks on Perioperative Pain in Gender Affirmation Top Surgery NCT04474366 | University of California, San Francisco | Phase 4 |
| Completed | i2TransHealth: Interdisciplinary, Internet-based Trans Health Care NCT04290286 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | Chest Dysphoria in Transmasculine Spectrum Adolescents NCT04195659 | Northwestern University | — |
| Completed | Effectiveness of Speech Therapy in Trans Women. NCT04708600 | University Ghent | N/A |
| Completed | The Strategic Use of Hyaluronic Acid Fillers and Neurotoxin to Influence Gender Perception in Transgender Indi NCT04478214 | Mountain Dermatology Specialists | — |
| Active Not Recruiting | Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy NCT05829928 | University of Pittsburgh | — |
| Completed | Fertility Desires and Reproductive Needs of Transgender People NCT03836027 | Central Hospital, Nancy, France | — |
| Completed | Voice Feminisation in Transgender Women NCT03899896 | Central Hospital, Nancy, France | — |
| Unknown | Transgender Cohort Study of Gender Affirmation and HIV-related Health NCT03595956 | Fenway Community Health | — |
| Unknown | TransCare - Genital Surgery for Trans Women in Centralized vs. Decentralized Health Care Delivery Settings NCT03872648 | Universitätsklinikum Hamburg-Eppendorf | — |
| Unknown | Gender Dysphoria Among Adolescents (Norwegian Title: Kjønnsdysfori Blant Ungdom) NCT03643120 | Oslo University Hospital | N/A |
| Unknown | Sexuality in Transmen During Hormone and Operative Treatment NCT03637920 | Medical University of Graz | — |
| Completed | Pubertal Blockade and Hormone Therapy in Transgender Youth NCT03557268 | University of Colorado, Denver | — |
| Terminated | Gender Identity and Own Body Perception NCT04374708 | University of California, Los Angeles | — |
| Recruiting | Effects of Cross-sex Hormone Treatment on Cardiac Function, Myocardial and Hepatic Fat Content NCT06245681 | Medical University of Vienna | — |
| Recruiting | ZEPHYR: A Study Evaluating Surgical Outcome After Implantation of the Zephyr ZSI 475 FTM Inflatable Penile Imp NCT04064671 | University Hospital, Ghent | — |
| Completed | An LGBT-Competency Program for Mental Health Professionals in Romania NCT03602222 | Rutgers University | N/A |
| Terminated | The Relation of GnRH Treatment to QTc Interval in Transgender Females NCT03078829 | University of California, San Francisco | — |
| Unknown | Cross-sex Hormone Therapy and Neuronal Plasticity NCT03651427 | Hospital de Clinicas de Porto Alegre | N/A |
| Unknown | Effects of Sex Steroids on the Serotonin System NCT02715232 | Medical University of Vienna | Phase 4 |
| Completed | Subcutaneous Testosterone Project NCT02229617 | University of British Columbia | Phase 1 / Phase 2 |