DM1

9 registered clinical trials studyying DM1 — 5 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy NCT07486934	Dyne Therapeutics	Phase 3
Enrolling By Invitation	Global Open-Label Extension Study of Del-desiran for the Treatment of DM1 NCT07008469	Avidity Biosciences, Inc.	Phase 3
Recruiting	The Spanish National Registry for Myotonic Dystrophy Type 1 NCT07385443	Fundació Institut Germans Trias i Pujol	—
Active Not Recruiting	Global Study of Del-desiran for the Treatment of DM1 NCT06411288	Avidity Biosciences, Inc.	Phase 3
Completed	Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients NCT05479981	Avidity Biosciences, Inc.	Phase 2
Recruiting	Remote Assessments and Genetic Determinants of Myotonic Dystrophy NCT07505342	University of Rochester	—
Completed	Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients NCT05027269	Avidity Biosciences, Inc.	Phase 1 / Phase 2
Recruiting	Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1) NCT03981575	Virginia Commonwealth University	—
Completed	Induction of Pluripotent Stem Cells From Human Fibroblasts of DM1 Patients NCT02084407	Institut de Myologie, France	N/A