| Terminated | POWER UP: Participating Online While Exercising to Recover Using Play NCT05308407 | M.D. Anderson Cancer Center | N/A |
| Active Not Recruiting | Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors NCT05081180 | EMD Serono Research & Development Institute, Inc. | Phase 1 |
| Recruiting | OH2 Oncolytic Viral Therapy in Central Nervous System Tumors NCT05235074 | Binhui Biopharmaceutical Co., Ltd. | Phase 1 / Phase 2 |
| Terminated | Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors NCT03050450 | Johns Hopkins All Children's Hospital | Phase 1 |
| Completed | Durvalumab in Pediatric and Adolescent Patients NCT02793466 | Leo Mascarenhas | Phase 1 |
| Completed | Study of BLZ-100 in Pediatric Subjects With CNS Tumors NCT02462629 | Blaze Bioscience Inc. | Phase 1 |
| Unknown | Pemetrexed and Temozolomide in Treating Patients With Relapsed Primary Central Nervous System Lymphoma （PCNSL） NCT01985451 | Rongjie Tao | Phase 2 |
| Completed | Bevacizumab in Recurrent Grade II and III Glioma NCT01164189 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Completed | Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours NCT01135563 | The Hospital for Sick Children | Phase 1 |
| Completed | Outcomes Study of Late Effects After Proton RT for Pediatric Tumors of the Brain, Head, and Neck NCT01067196 | University of Florida | — |
| Withdrawn | OXC401-PO1s/WVU 1309 - A Pilot Study of Fosbretabulin With Bevacizumab in Recurrent High-Grade Gliomas NCT01052363 | West Virginia University | Phase 1 |
| Completed | Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumo NCT00876993 | Johns Hopkins All Children's Hospital | Phase 1 |
| Unknown | Temozolomide, Nedaplatin, Vincristine, and Radiotherapy as First-line Treatment in Newly Diagnosed Primary CNS NCT01735747 | Rongjie Tao | Phase 2 |
| Terminated | Nuclear Imaging of Human CSF Flow Using Ga-67 Citrate and In-111 DTPA NCT00477503 | M.D. Anderson Cancer Center | Phase 1 |
| Completed | DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma NCT00899834 | St. Jude Children's Research Hospital | — |
| Unknown | Administration of High Dose Thiotepa and Melphalan With Autologous Hematopoietic Stem Cell Transplant in Child NCT00607984 | Rabin Medical Center | N/A |
| Terminated | Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma NCT00107471 | Children's Oncology Group | Phase 1 / Phase 2 |
| Completed | Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma NCT00400816 | The Cleveland Clinic | Phase 2 |
| Completed | Electroacupuncture in Treating Delayed Nausea and Vomiting in Patients Receiving Chemotherapy For Newly Diagno NCT00040911 | Children's Oncology Group | N/A |
| Withdrawn | Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma NCT00109798 | The Methodist Hospital Research Institute | N/A |
| Completed | Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Per NCT00047320 | Children's Oncology Group | Phase 2 |
| Completed | Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphom NCT00152126 | St. Jude Children's Research Hospital | N/A |
| Completed | Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Tr NCT00066248 | University of South Florida | Phase 2 |
| Completed | Assessing the Effectiveness of Individual Education Plans for Childhood Cancer Survivors NCT00945828 | University of Miami | N/A |
| Terminated | Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblas NCT00031590 | Children's Hospital of Philadelphia | Phase 2 |
| Terminated | Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma NCT00005812 | Dartmouth-Hitchcock Medical Center | Phase 2 |
| Completed | Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma NCT00003935 | Children's Oncology Group | Phase 1 |
| Completed | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma NCT00003625 | Children's Oncology Group | Phase 1 |
| Completed | Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnose NCT00003573 | Children's Oncology Group | Phase 2 |
| Completed | Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patient NCT00003203 | Children's Oncology Group | Phase 2 |
| Completed | Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord NCT00003141 | Children's Oncology Group | Phase 1 |
| Completed | A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects NCT00187226 | St. Jude Children's Research Hospital | Phase 2 |
| Completed | Combination Chemotherapy in Treating Children With Progressive Brain Tumors NCT00002944 | Children's Oncology Group | Phase 3 |
| Completed | Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma NCT00002875 | Children's Oncology Group | Phase 3 |
| Completed | Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors NCT00003096 | Children's Oncology Group | — |
| Completed | Clinical Studies of Gemcitabine-Oxaliplatin NCT00407433 | Gustave Roussy, Cancer Campus, Grand Paris | Phase 2 |